B154
BU224 hydrochloride
solid
Sinónimos:
2-(4,5-Dihydroimidazol-2-yl)quinoline hydrochloride
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Fórmula empírica (notación de Hill):
C12H11N3 · HCl
Peso molecular:
233.70
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Form:
solid
Quality level:
Servicio técnico
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Permítanos ayudarleform
solid
Quality Level
color
white
solubility
ethanol: 1.2 mg/mL, H2O: >16 mg/mL, 0.1 M NaOH: 24 mg/mL, 0.1 M HCl: >30 mg/mL
SMILES string
Cl[H].C1CN=C(N1)c2ccc3ccccc3n2
InChI
1S/C12H11N3.ClH/c1-2-4-10-9(3-1)5-6-11(15-10)12-13-7-8-14-12;/h1-6H,7-8H2,(H,13,14);1H
InChI key
DDFHQXAQWZWRSQ-UHFFFAOYSA-N
Biochem/physiol Actions
I2 Imidazoline receptor antagonist.
Features and Benefits
This compound is featured on the Imidazoline Binding Sites page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Disclaimer
Hygroscopic; store desiccated
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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A Diaz et al.
European journal of pharmacology, 333(1), 9-15 (1997-08-20)
In this electrophysiological study, the effect of BU-224 (2-(4,5-dihydroimidazol-2yl)-quinoline hydrochloride)), a novel high affinity imidazoline I2 receptor ligand, was tested on the responses of nociceptive neurones in the spinal dorsal horn. When applied spinally, akin to an intrathecal application (i.t.)
A L Hudson et al.
Annals of the New York Academy of Sciences, 881, 81-91 (1999-07-23)
Over several years our group has sought to synthesize and identify selective ligands for imidazoline (I) receptors, in particular the I2 binding site. As a consequence, [3H]2-(2-benzofuranyl)-2-imidazoline (2BFI) has proved extremely useful for binding and autoradiographic studies. More recently we
Kazunori Kawamura et al.
Nuclear medicine and biology, 45, 1-7 (2016-11-12)
A positron emission tomography (PET) probe with ultra-high specific radioactivity (SA) enables measuring high receptor specific binding in brain regions by avoiding mass effect of the PET probe itself. It has been reported that PET probe with ultra-high SA can
Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| B154-5MG | 04061832088808 |