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MilliporeSigma
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AV42656

Sigma-Aldrich

Anti-EGFL8 antibody produced in rabbit

IgG fraction of antiserum

Sinónimos:

Anti-C6orf8, Anti-DAQB-143M3.8, Anti-EGF-like-domain, multiple 8, Anti-FLJ44493, Anti-MGC44938, Anti-MGC59719, Anti-NG3

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

32 kDa

species reactivity

human, mouse, rat, pig, horse, rabbit

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... EGFL8(80864)

General description

EGF-like-domain, multiple 8 (EGFL8), an EGFL7 paralog, is downregulated in metastatic colorectal cancers (CRC) making it a potential prognostic marker for poor prognosis in CRC and advanced gastric cancer.

Specificity

Anti-EGFL8 polyclonal antibody reacts with pig, bovine, human, mouse, and rat EGF-like-domain, multiple 8 proteins.

Immunogen

Synthetic peptide directed towards the C terminal region of human EGFL8

Application

Anti-EGFL8 polyclonal antibody is used to tag EGF-like-domain, multiple 8 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role of EGF-like-domain, multiple 8 protein as a potential prognostic marker for gastrointestinal cancers such as gastric cancer and colorectal cancer.

Sequence

Synthetic peptide located within the following region: QAGAWVRAVLPVPPEELQPEQVAELWGRGDRIESLSDQVLLLEERLGACS

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Ik-Jin Song et al.
International journal of molecular medicine, 36(2), 541-550 (2015-06-23)
Epidermal growth factor (EGF)-like (EGFL) domain, a common structural module in numerous secreted or transmembrane proteins, is generally involved in protein-protein interactions. To date, several EGFL proteins have been identified and characterized, but little is known about EGFL domain 8

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