If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
A9415
Actinomycin D
from Streptomyces sp., suitable for cell culture, ≥95%
Sinónimos:
Cosmegen, Meractinomycin, Actinomycin C1, Actinomycin IV, Dactinomycin
Seleccione un Tamaño
| Talla/SKU | Disponibilidad | Precio |
|---|---|---|
2 mg | Envío estimado HOYdesdeMILWAUKEE | $82.40 |
5 mg | Envío estimado HOYdesdeMILWAUKEE | $127.00 |
10 mg | Envío estimado HOYdesdeMILWAUKEE | $244.00 |
25 mg | Envío estimado HOYdesdeMILWAUKEE | $532.00 |
Acerca de este artículo
biological source
Streptomyces sp.
Quality Segment
assay
≥95%
form
powder
technique(s)
cell culture | mammalian: suitable
mp
251-253
solubility
ethanol, DMSO: soluble (Stable in aqueous solutions at 2-8 °C.)
antibiotic activity spectrum
neoplastics
mode of action
DNA synthesis | interferes
storage temp.
2-8°C
SMILES string
CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3OC4=C(C)C(=O)C(N)=C(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)C4=Nc23)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]7CCCN7C1=O
InChI
1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1
InChI key
RJURFGZVJUQBHK-IIXSONLDSA-N
General description
Application
Biochem/physiol Actions
Preparation Note
Other Notes
Disclaimer
1 of 1
Este artículo | |||
|---|---|---|---|
| description from Streptomyces sp., suitable for cell culture, ≥95% | description from Streptomyces sp., ~98% (HPLC) | description Ready Made Solution, from Streptomyces sp., 2 mg/mL in DMSO | description from Streptomyces sp., ≥95% (HPLC) |
| antibiotic activity spectrum neoplastics | antibiotic activity spectrum neoplastics | antibiotic activity spectrum neoplastics | antibiotic activity spectrum neoplastics |
| technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) - | technique(s) - |
| mode of action DNA synthesis | interferes | mode of action DNA synthesis | interferes | mode of action DNA synthesis | interferes | mode of action DNA synthesis | interferes |
| Quality Level 300 | Quality Level 300 | Quality Level 200 | Quality Level 200 |
| form powder | form powder | form liquid, ready-to-use solution | form powder |
| assay ≥95% | assay ~98% (HPLC) | assay - | assay ≥95% (HPLC) |
Still not finding the right product?
Explore all of our products under Actinomycin D
Palabra de advertencia
Danger
Códigos de peligro
Indicaciones de precaución
Hazard Classifications
Acute Tox. 2 Oral - Carc. 1B - Repr. 1B
Clase de almacenamiento
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
¿Qué está pasando?
WGK 3
Punto de inflamación (°F)
Not applicable
Punto de inflamación (°C)
Not applicable
EPI (equipos de protección individual)
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
-
How can I determine the shelf life / expiration / retest date of this product?
1 answer-
Helpful?
-
-
How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Helpful?
-
-
What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Helpful?
-
-
What is the working concentration for Actinomycin D (Product No. A9415)?
1 answer-
For cell culture applications, actinomycin D is used as a selection agent and is used in banding techniques to differentiate between different regions of chromosomes. Suggested working concentrations is 1 μg/mL.
Helpful?
-
-
How do you recommend dissolving Product No. A9415 (Actinomycin D)?
1 answer-
Stock solutions of this product may be prepared at 10 mg/mL in either ethanol (EtOH) or dimethyl sulfoxide (DMSO).
Helpful?
-
-
How long are stock solutions of Actinomycin D (Product No. A9415) stable?
1 answer-
Stock solutions of this product in DMSO or ethanol should be stored in foil-wrapped vials at -20 °C. In DMSO, solution can be stored for up to 1 month at -20 °C. Do not store in glass vials.
Helpful?
-