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A7791

Sigma-Aldrich

N-Acetyl-D-lactosamine

≥98% (TLC)

Sinónimos:

β-D-Gal-(1→4)-D-GlcNAc, 2-Acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucopyranose, LN, N-Acetyl-4-O-(β-D-galactopyranosyl)-D-glucosamine

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About This Item

Fórmula empírica (notación de Hill):
C14H25NO11
Número de CAS:
32181-59-2
Peso molecular:
383.35
Beilstein/REAXYS Number:
96808
MDL number:
MFCD00063785
UNSPSC Code:
12352201
PubChem Substance ID:
24891280
NACRES:
NA.25

assay

≥98% (TLC)

form

powder

optical activity

[α]25/D 27.5 to 33.5 °, c = 0.5% (w/v) in water

technique(s)

thin layer chromatography (TLC): suitable

impurities

≤8% water

color

white

mp

170 -185  °C ((338 - 365 °F ))

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

storage temp.

−20°C

SMILES string

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@@H]1O

InChI

1S/C14H25NO11/c1-4(18)15-7-9(20)12(6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8+,9-,10+,11-,12-,13?,14+/m1/s1

InChI key

KFEUJDWYNGMDBV-RPHKZZMBSA-N

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application

N-Acetyl-D-lactosamine is used as a specific lectin target molecule in the identification and differentiation of sugar binding molecules such as the galectins. N-Acetyl-D-lactosamine is used in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.
Useful in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.

Preparation Note

Synthetic

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

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Meghan Rothenberger et al.
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HIV is produced in lymphoid tissues (LT) and stored on the follicular dendritic cell network in LT. When antiretroviral therapy is started, plasma viremia decays in 2 phases; the first within days of starting therapy and the second over weeks.
Moritz Augustin et al.
PLoS computational biology, 13(6), e1005545-e1005545 (2017-06-24)
The spiking activity of single neurons can be well described by a nonlinear integrate-and-fire model that includes somatic adaptation. When exposed to fluctuating inputs sparsely coupled populations of these model neurons exhibit stochastic collective dynamics that can be effectively characterized
Paulina Sindrewicz et al.
Scientific reports, 9(1), 11851-11851 (2019-08-16)
Galectins are involved in the regulation of divergent physiological and pathological processes and are increasingly recognized to play important roles in a number of diseases. However, a simple and effective way in assessing galectin-ligand interactions is lacking. Our examination of
Fumiko Suenaga et al.
Journal of immunology (Baltimore, Md. : 1950), 194(1), 398-406 (2014-11-26)
Graft-versus-host disease (GVHD) is a major risk factor for prolonged humoral immunodeficiency and vaccine unresponsiveness after allogeneic hematopoietic stem cell transplantation (allo-HSCT). However, the underlying mechanisms for this immunodeficiency are poorly understood. In this article, we describe previously overlooked impacts
Frank Liang et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 25(12), 2635-2647 (2017-09-30)
mRNA vaccines are rapidly emerging as a powerful platform for infectious diseases because they are well tolerated, immunogenic, and scalable and are built on precise but adaptable antigen design. We show that two immunizations of modified non-replicating mRNA encoding influenza
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