The molecular weight is not determined for this product. An internal note suggests the antifoam's molecular weight is approximately 3,000 daltons, but this is not verified.
A6426
Antiespumante 204
mixture of organic polyether dispersions
Sinónimos:
organic antifoam
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100 G
$53.60
500 G
$115.00
1 KG
$203.00
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100 G
$53.60
500 G
$115.00
1 KG
$203.00
About This Item
Productos recomendados
biological source
synthetic
Quality Level
form
liquid
technique(s)
microbiological culture: suitable
viscosity
400 cP(lit.)
density
1.01 g/cm3 at 25 °C (lit.)
storage temp.
room temp
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General description
Función antiespumante como un efectivo supresor de espuma.[1] El antiespumante 204 contiene componentes activos al 100 % y es una mezcla de dispersiones orgánicas de poliéter basadas en polipropileno sin silicona. No contiene aceite mineral. El antiespumante 204 puede ser considerado como un tensioactivo, pero no contiene otros tensioactivos. Este producto es sintético y no procede de fuentes de origen animal o vegetal. El antiespumante 204 puede esterilizarse repetidamente. Las propiedades de flujo del antiespumante 204 son tales que puede ser bombeado hasta un fermentador según necesidad. Para utilizar en medios microbiológicos, Sigma recomienda una concentración de partida comprendida entre el 0,005% y el 0,01%.
Application
El antiespumante 204 se ha utilizado:
Features and Benefits
- Tensioactivo muy versátil para su investigación en biología celular y bioquímica
- Adecuado para cultivo microbiológico
Other Notes
Contiene componentes activos al 100 % y es una mezcla de antiespumantes orgánicos distintos de la silicona en una dispersión poliol. Puede esterilizarse repetidamente.
Si desea más información sobre nuestra gama de productos bioquímicos, cumplimente este formulario.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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What is the molecular weight of this product? Mean and dispersion? We are trying to assess passage through membranes.
1 answer-
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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May i ask if you have the toxicological safety data (such as LD50) of Antifoam 204 (Cat # A6426)?
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The toxicological data can be found in Section 11 of the Safety Data Sheet. This document may be accessed by entering the product number in the SDS section at the link below: https://www.sigmaaldrich.com/documents-search?tab=sds
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I am using Antifoam 204 in vaccine fermentation process as an antifoaming agent. Regulatory expectation is to varify residual content of 204 in final product. Do you have any suggestion on which analytical method should one explore for such a characteriza
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This product is intended for research use only. It is not suitable for human or veterinary use. Unfortunately, a method for residual detection is not available. However, a brief search of the literature reveals that several methods may be deployed, including LC/MS/MS and LS/CAD. Please see the links below to review publications regarding testing for residual amounts of antifoam.
https://onlinelibrary.wiley.com/doi/pdf/10.1002/j.2050-0416.1977.tb06809.x
https://www.eurofinsus.com/media/447588/9207_residual_impurities_bioprocessing.pdf
https://www.bioprocessintl.com/process-monitoring-and-controls/analytical-strategies-for-monitoring-residual-impurities-encountered-in-bioprocessingResidual level tests for antifoam may require a dedicated piece of equipment due to the antifoam properties.
Various general recommendations may be of interest:
a. Use an antifoam sensor/ probe or pump to measure the amount of antifoam in solution
b. NMR
c. ViscosityHelpful?
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Quelle est la molécule du antifoam 204? Est ce un polyethylene glycol classique?
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Antifoam 204 contains 100% active components and is a mixture of organic non-silicone polypropylene-based polyether dispersions. It does not contain mineral oil. The exact composition is considered proprietary by the supplier.
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May I ask if you have the LD50 information of Antifoam 204 (Cat#A6426)?
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Unfortunately, there is no LD50 information available for this product. A brief search of the literature revealed a publication that reports an LD50 of > 5000 mg/kg in rats. Please see the link below to review this article:
https://www.sciencedirect.com/science/article/abs/pii/B9781774670088500092Helpful?
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