A4475

Anti-Annexin VII antibody, Mouse monoclonal

clone 203-217/6, purified from hybridoma cell culture

• Sinónimos: Synexin
• Número MDL: MFCD03792412
• Código UNSPSC: 12352203
• NACRES: NA.44

Propiedades

• origen biológico: mouse
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 203-217/6, monoclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 47-51 kDa
• reactividad de especies: mouse, canine, rat, chicken, bovine, human, rabbit
• técnicas: immunocytochemistry: suitable using methanol or 1% paraformaldehyde/0.1% glutaraldehyde; immunohistochemistry (frozen sections): suitable; microarray: suitable; western blot: 0.5-1 μg/mL using whole cell extract of culture mouse connective tissue (A9) cells.
• isotipo: IgG1
• Nº de acceso UniProt: P20073
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... ANXA7(310) ; mouse ... Anxa7(11750) ; rat ... Anxa7(155423)

Descripción

Descripción general

Annexin VII (synexin) is a membrane binding protein that localizes in the nucleus and cytosol. In humans and mice, Annexin VII is encoded by a single gene that has alternatively spliced cassette exons. As a result, two isoforms of molecular mass of 47kDa and 51kDa are expressed. These isoforms differ in their N-terminal region and also have distinct tissue-specific expression patterns.

Anti-Annexin VII antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the 203-217/6 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a recombinant mouse Annexin VII. The human annexin VII (ANXA7) is located on chromosome 10q21.

Especificidad

Mouse monoclonal anti-annexin VII antibody reacts with human, bovine, rabbit, dog, rat, mouse, and chicken Annexin VII.

Inmunógeno

recombinant mouse annexin VII.

Aplicación

Anti-Annexin VII antibody, Mouse monoclonal has been used in:

• western blotting
• immunocytochemistry
• immunohistochemistry

Acciones bioquímicas o fisiológicas

Antibodies reacting specifically with Annexin VII serve as an essential tool for the detection of this molecule in various cells. The human annexin VII (ANXA7) possesses a tumor suppressor role in prostate cancer. Hence it can be used an important biomarker along with syndecan-1 to predict the survival rates in prostate cancer patients.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable