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A4142

Azaserine

≥98% (TLC)

Sinónimos:

O-Diazoacetyl-L-serine

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A ustedes/SKUDisponibilidadPrecio
50 mg

Fecha estimada de envío07 de agosto de 2027desdeMILWAUKEE.

$299.00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C5H7N3O4
Número CAS:
Peso molecular:
173.13
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
EC Number:
204-061-6
Beilstein/REAXYS Number:
1726602
MDL number:

$299.00


Fecha estimada de envío07 de agosto de 2027. Detalles


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Quality Segment

assay

≥98% (TLC)

form

powder

color

off-white to yellow-green

antibiotic activity spectrum

fungi

mode of action

enzyme | inhibits

storage temp.

−20°C

SMILES string

N[C@@H](COC(=O)C=[N+]=[N-])C(O)=O

InChI

1S/C5H7N3O4/c6-3(5(10)11)2-12-4(9)1-8-7/h1,3H,2,6H2,(H,10,11)/t3-/m0/s1

InChI key

MZZGOOYMKKIOOX-VKHMYHEASA-N

General description

Chemical structure: amino acid derivatives

Application

Used in cell culture for the selection of HGPRT revertants.

Biochem/physiol Actions

Azaserine is an antibiotic and antifungal; it may also act as a tumor inducer. It is a structural analog of glutamine and competes with glutamine in binding to enzymes involved in purine biosynthesis. Azaserine inhibits purine biosynthesis by covalently reacting with cysteine residues in the enzyme active sites, such as in formylglycinamide ribonucleotide amidotransferase and PRPP amidotransferase. Azaserine can induce DNA damage via the formation of carboxymethylated bases and O6-methylguanine. Secretion of exo-1,3-β-glucanase and germ-tube formation of Candida albicans were inhibited by azaserine.

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Este artículo
A1164D2141C6880
description

≥98% (TLC)

description

Hybri-Max, γ-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma

description

powder

description

-

form

powder

form

lyophilized powder

form

powder

form

powder

assay

≥98% (TLC)

assay

-

assay

≥95% (HPLC)

assay

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

color

off-white to yellow-green

color

-

color

faint yellow, to yellow or tan

color

-

mode of action

enzyme | inhibits

mode of action

enzyme | inhibits

mode of action

enzyme | inhibits

mode of action

cell wall synthesis | interferes


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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