A3286

N-Acetil-D-glucosamina

BioReagent, suitable for cell culture

• Sinónimos: 2-Acetamido-2-desoxi-D-glucosa, D-GlcNAc
• Fórmula empírica (notación de Hill): C₈H₁₅NO₆
• Número de CAS: 7512-17-6
• Peso molecular: 221.21
• Beilstein/REAXYS Number: 1727589
• EC Number: 231-368-2
• MDL number: MFCD00061615
• UNSPSC Code: 12352201
• PubChem Substance ID: 24890757
• NACRES: NA.75

Propiedades

• product line: BioReagent
• Quality Level: 200
• assay: ≥95% (HPLC)
• form: powder
• technique(s): cell culture | mammalian: suitable
• mp: 211 °C (dec.) (lit.)
• storage temp.: −20°C
• SMILES string: CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
• InChI: 1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8?/m1/s1
• InChI key: OVRNDRQMDRJTHS-RTRLPJTCSA-N

Descripción

General description

N-Acetylglucosamine (GlcNAc), a derivative of glucose is a monosaccharide. It is a white powder and is mildly sweet. It melts at 221°C. GlcNAc is 25% soluble in water. It is present in bromelain, ricin agglutinin and abrus agglutinin, in plants. In humans, it is present in tissue plasminogen activator, growth factors and hormones.[1]

Application

N-Acetyl-D-glucosamine addition has been used:

• as a substrate to develop dot-blots[2]
• as a substrate to reveal alkaline phosphatase in the immunohistochemical analysis[1]
• to detect specific immune complexes in western blot analysis[3][4][5]

Biochem/physiol Actions

N-Acetylglucosamine (GlcNAc) oligomer may have the ability to initiate factors for canine polymorphonuclear cells (PMN) in vivo. It possesses wound healing and chemotactic activity.[2] GlcNAc and its derivatives are usually employed in preparing dietary supplements and also used in therapeutic development.[1]

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)