A214680
DMT-2′O-TC-rA(ib) Phosphoramidite
configured for PerkinElmer
Sinónimos:
DMT-2′O-TC-rA(ib) Amidite
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Quality Segment
assay
≥98% (31P-NMR), ≥98.0% (reversed phase HPLC)
technique(s)
oligo synthesis: suitable
impurities
≤-0.5% 31P-NMR P(III) impurites 145-155ppm (31P-NMR), ≤-0.5% Impurity 3′-TC Isomer (reversed phase HPLC)
compatibility
configured for PerkinElmer
nucleoside profile
base: adenosine
base protecting group: isobutyryl
2' protecting group: TC
5' protecting group: DMT
storage temp.
-10 to -25°C
SMILES string
S=C(N1CCS(CC1)(=O)=O)O[C@@H]2[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@H](O[C@H]2N3C4=C(N=C3)C(NC(C(C)C)=O)=NC=N4)COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7
InChI
1S/C49H61N8O10PS2/c1-32(2)46(58)54-44-41-45(52-30-51-44)56(31-53-41)47-43(66-48(69)55-24-27-70(59,60)28-25-55)42(67-68(64-26-12-23-50)57(33(3)4)34(5)6)40(65-47)29-63-49(35-13-10-9-11-14-35,36-15-19-38(61-7)20-16-36)37-17-21-39(62-8)22-18-37/h9-11,13-22,30
InChI key
JDHHUACDFJOZGR-LCVXBTAASA-N
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Este artículo | |||
|---|---|---|---|
| description configured for PerkinElmer | description configured for ABI | description - | description configured for ABI |
| assay ≥98% (31P-NMR), ≥98.0% (reversed phase HPLC) | assay ≥98% (31P-NMR), ≥98.0% (reversed phase HPLC) | assay ≥98.0% (reversed phase HPLC), ≥98% (31P-NMR) | assay ≥99% (31P-NMR), ≥99.0% (reversed phase HPLC) |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 300 |
| storage temp. -10 to -25°C | storage temp. -10 to -25°C | storage temp. -10 to -25°C | storage temp. -10 to -25°C |
| impurities ≤-0.5% 31P-NMR P(III) impurites 145-155ppm (31P-NMR), ≤-0.5% Impurity 3′-TC Isomer (reversed phase HPLC) | impurities ≤-0.5% Impurity 3′-TC Isomer (reversed phase HPLC), ≤-0.5% 31P-NMR P(III) impurites 145-155ppm (31P-NMR) | impurities ≤-0.5% 31P-NMR P(III) impurites 145-155ppm (31P-NMR), ≤-0.5% Impurity 3′-TC Isomer (reversed phase HPLC) | impurities ≤0.1% single unspecified Impurity (reversed phase HPLC), ≤3% residual Solvent content, ≤1.0% mA1 (reversed phase HPLC, DMT-rA(bz)me-DMT), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤0.3% mA3 (reversed phase HPLC, DMT-rA(bz)me), ≤0.3% mA2 (reversed phase HPLC, Hydrolysate), ≤0.3% water content (Karl Fischer) |
| technique(s) oligo synthesis: suitable | technique(s) oligo synthesis: suitable | technique(s) oligo synthesis: suitable | technique(s) oligo synthesis: suitable |
| nucleoside profile base: adenosine | nucleoside profile base: adenosine | nucleoside profile base: adenosine | nucleoside profile base: adenosine |
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