Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
90790
L-α-Hydroxyglutaric acid disodium salt
≥98.0% (GC)
Sinónimos:
(S)-2-Hydroxypentanedioic acid disodium salt, Disodium (S)-2-hydroxyglutarate
Iniciar sesión para ver los precios por organización y contrato.
Seleccione un Tamaño
Cambiar Vistas
| A ustedes/SKU | Disponibilidad | Precio |
|---|---|---|
10 mg | Envío estimado HOYdesdeMILWAUKEE | $105.00 |
50 mg | Envío estimado HOYdesdeMILWAUKEE | $364.00 |
Acerca de este artículo
Fórmula lineal:
C5H6O5Na2
Número CAS:
Peso molecular:
192.08
UNSPSC Code:
12352106
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5318042
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarleQuality Segment
assay
≥98.0% (GC)
form
powder or crystals
optical activity
[α]/D -8.5±1.5°, c = 1 in 0.1 M NaOH
impurities
≤6.0% water
relevant disease(s)
cancer
storage temp.
2-8°C
SMILES string
[O-]C(CC[C@@H](C([O-])=O)O)=O.[Na+].[Na+]
InChI
1S/C5H8O5.2Na/c6-3(5(9)10)1-2-4(7)8;;/h3,6H,1-2H2,(H,7,8)(H,9,10);;/q;2*+1/p-2/t3-;;/m0../s1
InChI key
DZHFTEDSQFPDPP-QTNFYWBSSA-L
General description
Application
L-α-Hydroxyglutaric acid disodium salt is suitable for use in collection buffer for increased recovery of hypoxia-inducible factor-1 α (HIF-1α), a marker of hypoxia in human tumors.[4] It is also suitable for the radiolabeled 5mC-5hmC conversion assay to study the effect of 2-HG on the TET family of methyl hydroxylases.[5]
Biochem/physiol Actions
L-alpha-Hydroxyglutaric acid accumulates as a result of a rare defect in L-2-HG dehydogenase, leading to the metabolic disorder L-2-hydroxyglutaric aciduria (L-2HGA). L-2HGA is associated with neuronal defects, leukodystrophy and linked to an increased risk of brain tumors.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
1 of 1
Este artículo | |||
|---|---|---|---|
| assay ≥98.0% (GC) | assay ≥95% (GC) | assay ≥95.0% (GC) | assay ≥98.0% (GC) |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| form powder or crystals | form powder | form powder or crystals | form powder or crystals |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| impurities ≤6.0% water | impurities - | impurities ≤6.0% water | impurities ≤6.0% water |
| relevant disease(s) cancer | relevant disease(s) - | relevant disease(s) - | relevant disease(s) - |
Still not finding the right product?
Explore all of our products under L-α-Hydroxyglutaric acid disodium salt
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
-
What is the Department of Transportation shipping information for this product?
1 answer-
Helpful?
-
-
Is Product 90790, L-α-Hydroxyglutaric acid disodium salt cell membrane permeable?
1 answer-
We have not tested the cell membrane permeability of Product 90790, L-α-Hydroxyglutaric acid disodium salt. A helpful reference discussing the use of L-α-Hydroxyglutaric acid disodium salt to treat zebrafish is listed below.Parng, C. et al., Neurotoxicology and Teratology, 28, 509-516 , (2006).
Helpful?
-