44213

Thromboplastin from rabbit

• Sinónimos: Thromboplastin, Factor III, Thrombokinase
• Número CAS: 72162-96-0
• UNSPSC Code: 12352202
• EC Number: 276-433-6
• NACRES: NA.25
• MDL number: MFCD00148638
• Form: lyophilized solid
• Biological source: rabbit

Propiedades

• biological source: rabbit
• form: lyophilized solid
• UniProt accession no.: P24055
• storage temp.: 2-8°C
• Gene Information: rabbit ... F3(100009127)

Descripción

Application

Thromboplastin from rabbit has been used:

• as a standard in tissue factor procoagulant activity assay (TF-PCA)
• in pulmonary embolism assay
• as a positive control in clotting assay using human plasma

Biochem/physiol Actions

Thromboplastin (Tissue factor) is a transmembrane protein, the chief in vivo activator of blood coagulation that leads to thrombin generation and fibrin deposition. It is also important in the activation of the coagulation protease cascade and is involved in the lethality of sepsis.,

Thromboplastin from rabbit might be used to produce disseminated intravascular coagulation (DIC) in animal models.

Packaging

One vial contains 3-4 mg thromboplastin.

Preparation Note

Reconstitute the content of 1 vial in 4 ml 10 mm CaCl₂

Información de seguridad

• Pictogramas: GHS08
• Palabra de advertencia: Danger
• Códigos de peligro: H334
• Indicaciones de precaución: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 1
• EPI (equipos de protección individual): Eyeshields, Gloves, type N95 (US)