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322M-1

Sigma-Aldrich

Podoplanin (D2-40) Mouse Monoclonal Antibody

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1 ML
$159.00
0.1 ML
$191.00
7 ML
$564.00
0.5 ML
$648.00
1 ML
$1,040.00
25 ML
$1,800.00

$159.00


Fecha estimada de envío12 de febrero de 2025


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1 ML
$159.00
0.1 ML
$191.00
7 ML
$564.00
0.5 ML
$648.00
1 ML
$1,040.00
25 ML
$1,800.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$159.00


Fecha estimada de envío12 de febrero de 2025


Solicitar un pedido a granel

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

D2-40, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (322M-14)
vial of 0.5 mL concentrate (322M-15)
bottle of 1.0 mL predilute (322M-17)
vial of 1.0 mL concentrate (322M-16)
bottle of 7.0 mL predilute (322M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:20-1:100

isotype

IgG1

control

tonsil

shipped in

wet ice

Storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... PDPN(10630)

General description

Podoplanin is a transmembrane mucoprotein (38 kD) recognized by the D2-40 monoclonal antibody. Podoplanin is selectively expressed in normal and malignant lymphatic endothelium, including Kaposi’s sarcomas. Podoplanin has also been shown to be expressed in epithelioid mesotheliomas and seminomas.

Quality


IVD

IVD

IVD

RUO

Linkage

Podoplanin Positive Control Slides, Product No. 322S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análisis (COA)

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Csaba Galambos et al.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 8(2), 181-189 (2005-02-19)
The distinction between lymphatic and other vascular vessels on microscopic sections is a challenging task. D2-40, a novel antibody, has been reported to be selective for lymphatic endothelium. We studied the specificity and sensitivity of D2-40 in pediatric vascular tumors
M Fukunaga
Histopathology, 46(4), 396-402 (2005-04-07)
To evaluate the expression of D2-40 in normal lymphatic endothelium and vascular tumours or tumour-like lesions of the skin and soft tissue. D2-40 is a novel monoclonal antibody to a Mr 40 000 O-linked sialoglycoprotein that reacts with a fixation-resistant
Nelson G Ordóñez
Advances in anatomic pathology, 13(2), 83-88 (2006-05-04)
Podoplanin is a transmembrane mucoprotein recognized by the recently commercially available D2-40 monoclonal antibody. Recent investigations have shown that podoplanin is selectively expressed in lymphatic endothelium as well as lymphangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable
Nelson G Ordóñez
Human pathology, 36(4), 372-380 (2005-05-14)
Recent investigations have shown that podoplanin and the D2-40 monoclonal antibody, which reacts with an oncofetal antigen present in fetal germ cells, are highly reliable lymphatic endothelial markers. The observation that both of these markers are also expressed in normal
Albert Y Chu et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 18(1), 105-110 (2004-09-25)
Although immunohistochemistry has proven to be valuable in the differentiation of epithelioid mesothelioma from pulmonary or metastatic adenocarcinoma, no single antibody has demonstrated absolute sensitivity or specificity in making this distinction. Using immunohistochemical analysis with D2-40, a recently available monoclonal

Questions

  1. What is the number of tests included in the following products:
    Podoplanin (D2-40) - 7 mL RTU (322M-18)
    H. pylori - 7 mL RTU (215A-78)

    1 answer
    1. Approximately 7 ml of volume will yield 60 to 70 tests on the Ventana system, accounting for potential losses during priming and aliquoting.

      Helpful?

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