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MilliporeSigma

30382

Sigma-Aldrich

Cytochalasin C from Metarrhizium anisopliae

≥97.0% (TLC)

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About This Item

Fórmula empírica (notación de Hill):
C30H37NO6
Número de CAS:
Peso molecular:
507.62
Beilstein/REAXYS Number:
1613194
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77

biological source

Metarrhizium anisopliae

assay

≥97.0% (TLC)

form

fibers
powder

solubility

methylene chloride: 5 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

C[C@@H]1C\C=C\[C@H]2[C@H](O)C(C)=C(C)C3[C@H](Cc4ccccc4)NC(=O)[C@@]23C(OC(C)=O)\C=C\[C@@](C)(O)C1=O

InChI

1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17,22-26,33,36H,10,16H2,1-5H3,(H,31,35)/b13-9+,15-14+/t17-,22+,23+,24-,25?,26-,29-,30-/m1/s1

InChI key

NAIODHJWOHMDJX-QMTXKCDBSA-N

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Other Notes

Structure of cytochalasins and cytochalasin B binding sites in human erythrocyte membranes

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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H Haimoto et al.
The American journal of pathology, 121(2), 185-191 (1985-11-01)
To elucidate the changes of ultrastructural localization of S-100 protein during lipolysis in adipocytes, an immunoelectron-microscopic study was performed. Epididymal fat pads from Wistar rats were incubated in the buffer with or without 10 microM epinephrine. Before incubation with epinephrine
M Varedi et al.
Journal of cellular physiology, 172(2), 192-199 (1997-08-01)
Cytoskeleton not only controls cell morphology but also regulates cell growth, migration, differentiation, and gene expression, events which are fundamental to embryogenesis, carcinogenesis, and wound healing. We have recently reported that reorganization of cytoskeleton induces expression of mRNA for transforming
J Thyberg et al.
Virchows Archiv. B, Cell pathology including molecular pathology, 59(1), 1-10 (1990-01-01)
The transition of adult rat aortic smooth muscle cells from a contractile to a synthetic phenotype during the first week of primary culture on a substrate of fibronectin in serum-free medium was studied by light and electron microscopy. The weak
V G Lukashin et al.
Morfologiia (Saint Petersburg, Russia), 118(4), 41-45 (2003-03-13)
Colchicine and cytochalasine C exert modifying action on tissue receptors of urinary bladder of the frog. Under the effect of cytochalasine the period of vital staining of receptors were changed. Latent period of decoloration grew 37-56% longer while the period
Jeffrey C Nolz et al.
Journal of immunology (Baltimore, Md. : 1950), 179(2), 1104-1112 (2007-07-10)
TCR/CD28 engagement triggers the initiation of a variety of signal transduction pathways that lead to changes in gene transcription. Although reorganization of the actin cytoskeleton is required for T cell activation, the molecular pathways controlled by the actin cytoskeleton are

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