EX-CELL 610-HSF is a low-protein (11 mg/L) serum-free medium. Originally developed to support the growth of hybrid cells in culture, it has been shown to support a wide range of cells including lymphoid and epithelial cells and B cell hybridomas of murine, rat and human origin. EX-CELL 610-HSF has been used in stationary culture systems and in large-scale bioreactors. In both types of culture, the production of cellular products, particularly monoclonal antibodies, has been shown to equal or exceed levels seen when the same cells are cultured in the presence of Fetal Bovine Serum (FBS).
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EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
We introduce a new concept and potentially general platform for antibody (Ab) purification that does not rely on chromatography or specific ligands (e.g., Protein A); rather, it makes use of detergent aggregates capable of efficiently capturing Ab while rejecting hydrophilic
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