121R-1
CD21 (EP3093) Rabbit Monoclonal Primary Antibody
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1 ML
$208.00
0.1 ML
$264.00
7 ML
$473.00
0.5 ML
$588.00
1 ML
$854.00
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Cambiar Vistas
1 ML
$208.00
0.1 ML
$264.00
7 ML
$473.00
0.5 ML
$588.00
1 ML
$854.00
About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
Productos recomendados
origen biológico
rabbit
Nivel de calidad
100
500
conjugado
unconjugated
forma del anticuerpo
culture supernatant
tipo de anticuerpo
primary antibodies
clon
EP3093, monoclonal
descripción
For In Vitro Diagnostic Use in Select Regions (See Chart)
Formulario
buffered aqueous solution
reactividad de especies
human
envase
vial of 0.1 mL concentrate (121R-14)
vial of 0.5 mL concentrate (121R-15)
bottle of 1.0 mL predilute (121R-17)
vial of 1.0 mL concentrate (121R-16)
bottle of 7.0 mL predilute (121R-18)
fabricante / nombre comercial
Cell Marque®
técnicas
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
isotipo
IgG
control
tonsil
Condiciones de envío
wet ice
temp. de almacenamiento
2-8°C
visualización
membranous
Información sobre el gen
human ... CR2(1380)
Categorías relacionadas
Descripción general
CD21 (also known as complement receptor 2 (CR2), C3d receptor, or EBV receptor) is a 140 kDa membrane protein on B-lymphocytes to which the Epstein-Barr virus (EBV) binds during infection of these cells.[1] The antigen is absent on T-lymphocytes, monocytes, and granulocytes.[2][3]
Anti-CD21 is useful in the identification of follicular dendritic cell matrix found in normal lymph node and tonsillar tissue. This antibody also labels follicular dendritic cell sarcomas.[2][4][5] Anti-CD21 is valuable in differentiating follicular lymphoma with marginal zone differentiation from marginal zone lymphoma with follicular involvement. It also plays a role in separating among nodular lymphocyte predominant Hodgkin lymphoma, lymphocyte-rich classic Hodgkin lymphoma, and T-cell/histiocyte-rich B-cell lymphoma in combination with other B-cell and T-cell markers.[6]Anti-CD21 is also useful in identifying abnormal follicular dendritic cell pattern in angioimmunoblastic T-cell lymphoma and follicular T-cell lymphoma.[7]
Anti-CD21 is useful in the identification of follicular dendritic cell matrix found in normal lymph node and tonsillar tissue. This antibody also labels follicular dendritic cell sarcomas.[2][4][5] Anti-CD21 is valuable in differentiating follicular lymphoma with marginal zone differentiation from marginal zone lymphoma with follicular involvement. It also plays a role in separating among nodular lymphocyte predominant Hodgkin lymphoma, lymphocyte-rich classic Hodgkin lymphoma, and T-cell/histiocyte-rich B-cell lymphoma in combination with other B-cell and T-cell markers.[6]Anti-CD21 is also useful in identifying abnormal follicular dendritic cell pattern in angioimmunoblastic T-cell lymphoma and follicular T-cell lymphoma.[7]
Calidad
 IVD |  IVD |  IVD |  RUO |
Ligadura / enlace
CD21 Positive Control Slides, Product No. 121S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Forma física
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Nota de preparación
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Otras notas
For Technical Service please contact: 800-665-7284 or email: [email protected]
Información legal
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Shih-Sung Chuang et al.
International journal of hematology, 91(4), 687-691 (2010-03-04)
Angioimmunoblastic lymphoma (AITL) is a nodal peripheral T-cell lymphoma characterized by a proliferation of arborizing vessels and hyperplastic follicular dendritic cells as well as a polymorphous lymphoid infiltrate including neoplastic cells with clear cytoplasm. Adult T-cell leukemia/lymphoma (ATLL) is caused
A C Chan et al.
Histopathology, 38(6), 510-518 (2001-06-26)
Hyaline-vascular Castleman's disease (HVCD) and follicular dendritic cell (FDC) sarcoma occurring in the nasopharynx are both extremely rare. We report the first case of transformation of the former into the latter as documented by sequential biopsies. The steps involved in
W Cheuk et al.
The American journal of surgical pathology, 25(6), 721-731 (2001-06-08)
Follicular dendritic cell (FDC) tumors are uncommon neoplasms that can involve lymph nodes or extranodal sites. They can exhibit a broad spectrum of histologic appearances and behavior, but the intra-abdominal ones usually pursue an aggressive course. The purpose of this
Kong-Chao Chang et al.
The Journal of pathology, 201(3), 404-412 (2003-11-05)
Follicular dendritic cells (FDCs) in reactive germinal centres (GCs) show modulated expression of antigens indicative of step-wise maturation from more undifferentiated stroma. The present study compared the expression of FDC markers CD21, CD23, CD35, and chemokine CXCL13 and the stromal
S A Pileri et al.
Histopathology, 41(1), 1-29 (2002-07-18)
Neoplasms of histiocytes and dendritic cells are rare, and their phenotypic and biological definition is incomplete. Seeking to identify antigens detectable in paraffin-embedded sections that might allow a more complete, rational immunophenotypic classification of histiocytic/dendritic cell neoplasms, the International Lymphoma
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