Y0002005

Rotigotine hydrochloride

European Pharmacopoeia (EP) Reference Standard

• Sinónimos: (−)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol hydrochloride, (−)-N 0437, N 0923, Neupro, SPM 962
• Fórmula empírica (notación de Hill): C₁₉H₂₅NOS·HCl
• Número de CAS: 125572-93-2
• Peso molecular: 351.93
• Número MDL: MFCD00906149
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: rotigotine
• fabricante / nombre comercial: EDQM
• Formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: Cl.CCCN(CCc1cccs1)[C@H]2CCc3c(O)cccc3C2
• InChI: 1S/C19H25NOS.ClH/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21;/h3-7,13,16,21H,2,8-12,14H2,1H3;1H/t16-;/m0./s1
• Clave InChI: CEXBONHIOKGWNU-NTISSMGPSA-N

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Rotigotine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Acciones bioquímicas o fisiológicas

Rotigotine is a dopamine receptor agonist with preference for D₃ receptors over D₂ and D₁. As such, it is an effective anti-Parkinsonian agent.

Rotigotine is a dopamine receptor agonist with preference for D₃ receptors over D₂ and D₁. As such, it is an effective anti-Parkinsonian agent. Racemic rotigotine is about 50 times as potent as quinpirole, the gold standard D₂ agonist.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable