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Y0001442

N-[(cis-4-Isopropylcyclohexyl)carbonyl]-D-phenylalanine

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

N-[[cis-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine

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About This Item

Fórmula empírica (notación de Hill):
C19H27NO3
Número de CAS:
105816-06-6
Peso molecular:
317.42
Código UNSPSC:
41116107
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

nateglinide

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

N-[(cis-4-Isopropylcyclohexyl)carbonyl]-ᴅ-phenylalanine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

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Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Ranee Chatterjee et al.
American journal of hypertension, 26(6), 723-726 (2013-02-19)
Low and low-normal serum potassium is associated with an increased risk of diabetes. We hypothesized that the protective effect of valsartan on diabetes risk could be mediated by its effect of raising serum potassium. We analyzed data from the Nateglinide
F Zheng et al.
Journal of endocrinological investigation, 36(7), 489-496 (2013-01-18)
Recent studies highlight an important role of ghrelin in glucose homeostasis, while the association between ghrelin regulation and glucose fluctuation is unclear. We compared the effects of two postprandial hypoglycemic agents on ghrelin response and determined the contribution of ghrelin
Jin-Kui Yang et al.
Clinical drug investigation, 33(3), 185-191 (2013-01-23)
Diabetes mellitus has become a major public health problem in China. This open-label, prospective, multicentre, post-marketing surveillance study was conducted to investigate the efficacy and safety of nateglinide in combination with metformin in Chinese patients with type 2 diabetes (T2DM).
Subhash S Vaghani et al.
Current drug delivery, 9(6), 628-636 (2012-03-29)
In current research, chitosan was reacted with mono-chloroacetic acid under alkaline condition to prepare carboxymethyl chitosan (CMCTs). The degree of substitution (Ds) on prepared CMCTs was found to be 0.68. CMCTs was used as a potential carrier for pH specific
Yubing Zhu et al.
Clinical therapeutics, 34(7), 1505-1510 (2012-06-26)
Nateglinide, N-(trans-4-isopropylcyclohexyl-carbonyl)-d-phenylalanine, is a potent insulin secretagogue designed to restore early-phase insulin secretion. It increases pancreatic insulin secretion by competitively binding to sulfonylurea receptors inhibiting adenosine triphosphate-sensitive potassium channels and thus reducing blood glucose levels. The drug has a rapid
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