PHR1504

3,3′,5-Triyodo-L-tironina

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: O-(4-Hidroxi-3-yodofenil)-3,5-diyodo-L-tirosina, Liotironina, T₃
• Fórmula empírica (notación de Hill): C₁₅H₁₂I₃NO₄
• Número de CAS: 6893-02-3
• Peso molecular: 650.97
• Beilstein/REAXYS Number: 2710227
• EC Number: 229-999-3
• MDL number: MFCD00002593
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823425
• NACRES: NA.24

Propiedades

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to USP 1368008
• API family: liothyronine
• form: solid
• CofA: current certificate can be downloaded
• packaging: pkg of 500 mg
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 234-238 °C (lit.)
• application(s): pharmaceutical (small molecule)
• storage temp.: 2-8°C
• SMILES string: N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O
• InChI: 1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1
• Inchi Key: AUYYCJSJGJYCDS-LBPRGKRZSA-N
• Gene Information: human ... THRA(7067) , THRB(7068)

Descripción

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2088 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Información de seguridad

• Pictograms: GHS08
• signalword: Danger
• hcodes: H372
• pcodes: P260 - P264 - P270 - P314 - P501
• Hazard Classifications: STOT RE 1
• target_organs: Thyroid,Cardio-vascular system,Kidney
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable