PHR1030

DL-α-Tocopherol acetate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: DL-α-Tocopherol acetate, Vitamin E acetate, all-rac-α-Tocopheryl acetate
• Fórmula empírica (notación de Hill): C₃₁H₅₂O₃
• Número de CAS: 7695-91-2
• Peso molecular: 472.74
• Beilstein/REAXYS Number: 97512
• EC Number: 231-710-0
• MDL number: MFCD00072042
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823060
• NACRES: NA.24

Propiedades

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to Ph. Eur. T1600000; traceable to USP 1667701
• API family: tocopherol
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• density: 0.96 g/mL at 20 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1
• InChI: 1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
• InChI key: ZAKOWWREFLAJOT-CEFNRUSXSA-N

Descripción

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

Application

α-Tocopheryl acetate may be used as an internal standard in the determination of α-tocopherol in human serum or plasma samples using high performance chromatography (HPLC).[1][2] It may also be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique.[3]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC1696 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

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Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: No data available
• flash_point_c: No data available