PHL82542
Fisetin
phyproof® Reference Substance
Sinónimos:
3,3′,4′,7-Tetrahydroxyflavone, 5-Desoxyquercetin, Cotinin, Fiestin, Fietin
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About This Item
Fórmula empírica (notación de Hill):
C15H10O6
Número de CAS:
Peso molecular:
286.24
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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grade
primary reference standard
product line
phyproof® Reference Substance
assay
≥90.0% (HPLC)
manufacturer/tradename
PhytoLab
application(s)
food and beverages
format
neat
InChI
1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H
InChI key
XHEFDIBZLJXQHF-UHFFFAOYSA-N
Categorías relacionadas
General description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
application
- Fisetin anti-inflammatory and antioxidative properties: Fisetin reduces inflammation and oxidative stress in deep vein thrombosis, signaling via the MAPK and NRF2 pathways, highlighting its potential as an anti-inflammatory agent and its importance in managing thrombotic disorders (Liu and Lu, 2024).
- Fisetin in drug delivery system enhancement: A mechanochemical method improves fisetin′s solubility and biological activity, suggesting its utility in creating effective drug delivery systems that enhance the therapeutic effects of fisetin, particularly relevant in flavonoid research for increased bioavailability (Rosiak et al., 2024).
- Fisetin combination therapy for neuropathic pain: Utilizing fisetin with other treatments like pregabalin and gabapentin shows effectiveness in managing neuropathic pain, demonstrating fisetin′s role in enhancing pain management therapies and its potential in neuropharmacology (Karabacak et al., 2024).
- Fisetin in neurodegenerative disease research: Fisetin interacts with gut microbiota to offer a novel therapeutic approach in preventing and treating neurodegenerative diseases like Parkinson′s, underscoring its role in neuroprotective dietary interventions and the development of nutraceuticals (Yao et al., 2024).
- Fisetin in cardiovascular disease management: Fisetin suppresses atherosclerosis in apolipoprotein E knockout mice by inhibiting ferroptosis-related oxidative stress, indicating its potential use as a therapeutic agent in cardiovascular disease through modulation of oxidative stress pathways (Jiang et al., 2024).
Legal Information
phyproof is a registered trademark of PhytoLab GmbH & Co. KG
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Vanesa A Muñoz et al.
Photochemistry and photobiology, 96(4), 815-825 (2020-01-09)
In this work, the flavonol fisetin was selected in order to study its reactivity against Cu(II), a metal ion of interest in biological media and industry. The stoichiometry and apparent formation constant of the complex in ethanolic medium at 25°C
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