D1900000

Digoxin

European Pharmacopoeia (EP) Reference Standard

• Sinónimos: 12β-Hydroxydigitoxin
• Fórmula empírica (notación de Hill): C₄₁H₆₄O₁₄
• Número de CAS: 20830-75-5
• Peso molecular: 780.94
• Beilstein: 77011
• Número MDL: MFCD00003674
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329798713
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: digoxin
• fabricante / nombre comercial: EDQM
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• cadena SMILES: C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]2[C@@H](O)C[C@@H](O[C@@H]2C)O[C@H]3[C@@H](O)C[C@@H](O[C@@H]3C)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5C[C@@H](O)[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4
• InChI: 1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1
• Clave InChI: LTMHDMANZUZIPE-PUGKRICDSA-N
• Información sobre el gen: human ... ATP1A1(476) , ATP1A2(477) , ATP1A3(478) , ATP1A4(480) , ATP1B1(481) , ATP1B2(482) , ATP1B3(483) , FXYD2(486)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Digoxin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Acciones bioquímicas o fisiológicas

A cardiac glycoside, substrate for Pgp, upregulates Pgp expression and down regulates SXR (Steroid Xenobiotic Receptor).

A cardiac glycoside, substrate for Pgp.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H300,H331,H373
• Consejos de prudencia: P260 - P264 - P271 - P301 + P310 - P304 + P340 + P311 - P314
• Clasificaciones de peligro: Acute Tox. 2 Oral - Acute Tox. 3 Inhalation - STOT RE 2
• Código de clase de almacenamiento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3