A0200000

Acetylsalicylic acid

European Pharmacopoeia (EP) Reference Standard

• Sinónimos: 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin
• Fórmula lineal: 2-(CH₃CO₂)C₆H₄CO₂H
• Número CAS: 50-78-2
• Peso molecular: 180.16
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329770581
• MDL number: MFCD00002430
• Beilstein/REAXYS Number: 779271

Propiedades

• grade: pharmaceutical primary standard
• API family: aspirin
• manufacturer/tradename: EDQM
• mp: 134-136 °C (lit.)
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: CC(=O)Oc1ccccc1C(O)=O
• InChI: 1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
• InChI key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• Gene Information: human ... PTGS1(5742), PTGS2(5743)

Descripción

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Acetylsalicylic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS07
• Palabra de advertencia: Warning
• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 1
• Punto de inflamación (°F): 482.0 °F
• Punto de inflamación (°C): 250 °C
• Códigos de peligro: H302,H412
• Indicaciones de precaución: P264 - P270 - P273 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3