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91214

Supelco

Isofraxidin

analytical standard

Sinónimos:

6,8-Dimethoxyumbelliferone, 7-Hydroxy-6,8-dimethoxychromen-2-one, 7-Hydroxy-6,8-dimethoxycoumarin

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About This Item

Fórmula empírica (notación de Hill):
C11H10O5
Número de CAS:
486-21-5
Peso molecular:
222.19
Beilstein/REAXYS Number:
202652
MDL number:
MFCD00221757
UNSPSC Code:
85151701
PubChem Substance ID:
329770006
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤5.0% water

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

COc1cc2C=CC(=O)Oc2c(OC)c1O

InChI

1S/C11H10O5/c1-14-7-5-6-3-4-8(12)16-10(6)11(15-2)9(7)13/h3-5,13H,1-2H3

InChI key

HOEVRHHMDJKUMZ-UHFFFAOYSA-N

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General description

Isofraxidin is a major active constituent, isolated from Sarcandra glabra plant with a variety of biological properties such as antifatigue, antistress, anticancer, immunoaccomondating and cholagogic effects.[1]

Application

Isofraxidin may be used as an analytical reference standard for the separartion and quantification of the analyte in Sarcandra glabra plant[1] and Acanthopanax senticosus Harms[2] using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
BCCH4736
BCCF6368
BCCD2763
BCCB6662
BCCB8654

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Xiaofeng Niu et al.
International immunopharmacology, 14(2), 164-171 (2012-07-18)
Isofraxidin (IF) is a Coumarin compound that can be isolated from medicinal plants, such as Sarcandra glabra (Thunb.). Nakai is widely used in Asian countries for the treatment of anti-bacterial, anti-inflammatory and anti-tumour action. The present investigation was designed to
J H Kwak et al.
Journal of natural products, 64(8), 1081-1083 (2001-08-25)
Four new coumarin monoterpene ethers, artekeiskeanols A-D (1-4), and three known coumarins, isofraxidin, fraxidin, and daphnoretin, were isolated from the whole plants of Artemisia keiskeana. All structures were determined from spectral data, and that of artekeiskeanol A (1) was confirmed
Jiaqin Liu et al.
Bioorganic & medicinal chemistry, 12(2), 469-474 (2004-01-16)
This study was designed to examine the interaction of isofraxidin with human serum albumin (HSA) under physiological conditions with drug concentrations in the range of 3.3 x 10(-6) mol L(-1)-3.0x10(-5) mol L(-1) and HSA concentration at 1.5 x 10(-6) mol
T Yamazaki et al.
Toxicology in vitro : an international journal published in association with BIBRA, 21(8), 1530-1537 (2007-06-15)
(+)-Syringaresinol-di-O-beta-D-glucoside (SR), syringin, and isofraxidin isolated from the stem bark of Acanthopanax senticosus Harms are its major constituents. The present work was undertaken to analyze effects of these compounds on inflammatory functions in SW982 human synovial sarcoma cell system. When
Hui Sun et al.
Journal of separation science, 30(18), 3120-3126 (2007-11-17)
An HPLC with SPE method has been developed for analysis of constituents in rat blood after oral administration of the extract of Acanthopanax senticosus (ASE). The plasma sample was prepared by SPE method equipped with Oasis HLB cartridge (3cc, 60
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