TEPP (Tetraethyl pyrophosphate, Pestanal) is highly toxic in nature both by skin absorption and inhalation. It is an organic phosphate pesticide, acting acts as an inhibitor of cholinesterase. It is soluble in water and is slowly decomposed by water. It may be found as a dry mixture or in the liquid state.
Aplicación
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Información legal
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Journal of pharmaceutical sciences, 83(10), 1477-1481 (1994-10-01)
An O-(saccharinylmethyl) prodrug was synthesized to improve the poor oral potency of the phenolic drug 17 beta-estradiol. This O-(imidomethyl) type of prodrug was designed to undergo chemical hydrolysis and to be a poor substrate for enzymatic hydrolysis. At 37 degrees
Reversal of the actions of tetraethyl pyrophosphate in surviving mammalian tissue.
B B ROY et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 89(2), 255-258 (1955-06-01)
Studies on the mechanism of action of DFP and TEPP.
B P McNAMARA et al.
The Journal of pharmacology and experimental therapeutics, 110(2), 232-240 (1954-02-01)
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