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MilliporeSigma
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Documentos clave

10981

Supelco

Polyvinyl alcohol mounting medium with DABCO®, antifading

pH 8.7

Sinónimos:

PVA-DABCO®

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100 ML
$205.00

$205.00


Fecha estimada de envío06 de mayo de 2025DesdeSAINT LOUIS


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100 ML
$205.00

About This Item

Código UNSPSC:
12000000
NACRES:
NA.25

$205.00


Fecha estimada de envío06 de mayo de 2025DesdeSAINT LOUIS


Solicitar un pedido a granel

índice de refracción

n20/D 1.377

Nivel de calidad

pH

8.7

densidad

1.08 g/mL at 20 °C

idoneidad

in accordance for application

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

Forma física

Aqueous solution containing tris(hydroxymethyl)aminomethane, tris(hydroxymethyl)aminomethane hydrochloride, polyvinyl alcohol 22000, glycerol, and 1,4-diazabicyclo[2.2.2]octane

Información legal

DABCO is a registered trademark of Air Products & Chemicals, Inc.

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Referencia del producto
Descripción
Precios

Pictogramas

Corrosion

Palabra de señalización

Danger

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Eye Dam. 1

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

212.0 °F - closed cup

Punto de inflamabilidad (°C)

100 °C - closed cup

Equipo de protección personal

Eyeshields, Faceshields, Gloves


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Zurine De Miguel et al.
Molecular psychiatry, 24(8), 1178-1188 (2018-01-10)
Chronic stress is a recognized risk factor for psychiatric and psychological disorders and a potent modulator of adult neurogenesis. Numerous studies have shown that during stress, neurogenesis decreases; however, during the recovery from the stress, neurogenesis increases. Despite the increased
Laisel Martinez et al.
Journal of immunology (Baltimore, Md. : 1950), 205(9), 2545-2553 (2020-09-18)
Pharmacological activation of integrin CD11b/CD18 (αMβ2, Mac-1, and CR3) shows anti-inflammatory benefits in a variety of animal models of human disease, and it is a novel therapeutic strategy. Reasoning that genetic models can provide an orthogonal and direct system for
Alejandra Rodriguez Celin et al.
PloS one, 10(1), e0116343-e0116343 (2015-01-31)
The developing chick optic tectum is a widely used model of corticogenesis and angiogenesis. Cell behaviors involved in corticogenesis and angiogenesis share several regulatory mechanisms. In this way the 3D organizations of both systems adapt to each other. The consensus
Sierra Simpson et al.
eNeuro, 7(3) (2020-04-29)
Substance use disorders have a complex etiology. Genetics, the environment, and behavior all play a role in the initiation, escalation, and relapse of drug use. Recently, opioid use disorder has become a national health crisis. One aspect of opioid addiction
Melina Rapacioli et al.
BMC neuroscience, 13, 117-117 (2012-10-04)
Sonic hedgehog (Shh)/Gli pathway plays an important regulatory role on the neuroepithelial cells (NEc) proliferation in the dorsal regions of the developing vertebrate Central Nervous System. The aim of this paper was to analyze the effect of the Shh/Gli signaling

Questions

1–10 of 10 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. What are the instructions for using Polyvinyl Alcohol with DABCO 10971?

    1 answer
    1. There is no available information regarding using Polyvinyl Alcohol with DABCO 10971. Basic information is available that Polyvinyl Alcohol solution is ready to use as it comes from the bottle and should be stored at a temperature of 2-8°C and is important to bring the aqueous mounting media to room temperature before use.

      Helpful?

  4. After mounting the slides should be stored at room temperature or is better to have them at 2-8° or frozen at -20°C?

    1 answer
    1. After applying the mounting medium, slides should be stored at 4°C.

      Helpful?

  5. How does the use of aqueous Polyvinyl alcohol mounting medium with DABCO®, Product 10981, with an anti-fade agent differ from the use of a standard aqueous mounting media?

    1 answer
    1. The anti-fade agent used in product 10981 will result in an initial drop in the intensity of the fluorescence.  Once the drop in fluorescence has occurred, the remaining fluorescence is not prone to rapid photo bleaching.

      Helpful?

  6. Polyvinyl alcohol mounting medium with DABCO®, Product 10981, has gelled during refrigeration.  Is the product still usable?

    1 answer
    1. Yes, the product is still usable after gelling.  The product will however need to be reheated to around 50 degrees Celsius or higher.  It may take some time for the product to turn back into a liquid.

      Helpful?

  7. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  8. Is Polyvinyl alcohol mounting medium with DABCO®, Product 10981, a permanent mounting media?

    1 answer
    1. No. This is considered an aqueous mounting media.  Although an antifade agent is included in the formulation, the fluorescence will eventually fade.

      Helpful?

  9. Can clear finger nail polish be used to replace Polyvinyl alcohol mounting medium with DABCO®, Product 10981, to seal the edges of the coverslips?

    1 answer
    1. Anecdotal evidence suggests that permanent mounting medias do a better job of stopping evaporation of the aqueous mounting media. Clear finger nail polish has been used by some labs for sealing the edges of the coverslip.  We are unaware of any formal studies which have been performed that would document which product gives the better performance.

      Helpful?

  10. Is it necessary to seal the slides after coverslipping?

    1 answer
    1. No. The slides do not require sealing after coverslipping. However sealing the edges of the coverslip with a permanent mounting media such as DPX will prevent the gradual formation of air bubbles as the aqueous mounting media gradually dries.

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