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24-1270

Sigma-Aldrich

1,10-Phenanthroline monohydrate

JIS special grade, ≥99.0%

Sinónimos:

o-Phenanthroline monohydrate

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About This Item

Fórmula empírica (notación de Hill):
C12H8N2 · H2O
Número de CAS:
5144-89-8
Peso molecular:
198.22
Beilstein/REAXYS Number:
4008096
EC Number:
200-629-2
MDL number:
MFCD00149973
UNSPSC Code:
12352200
PubChem Substance ID:
329752577

grade

JIS special grade

assay

≥99.0%

form

powder

availability

available only in Japan

mp

100-104 °C (lit.)

solubility

water: soluble

SMILES string

O.c1cnc2c(c1)ccc3cccnc23

InChI

1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2

InChI key

PPQJCISYYXZCAE-UHFFFAOYSA-N

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Application

When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.

Biochem/physiol Actions

Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

hcodes

H301,H410

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
U8068
U5934
U9570
U1033
A7271

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Ayman A Gouda et al.
Chemistry Central journal, 2, 7-7 (2008-04-16)
Etodolac (ETD) is a non-steroidal anti-inflamatory antirheumatic drug. A survey of the literature reveals that there is no method available for the determination of ETD in pure form and pharmaceutical formulations by oxidation-reduction reactions. We describe three simple, sensitive and
Linlin Yang et al.
Analytical biochemistry, 492, 56-62 (2015-09-26)
We demonstrate a novel protocol for sensitive in situ label-free electrochemical detection of DNA hybridization based on copper complex ([Cu(phen)2](2+), where phen = 1,10-phenanthroline) and graphene (GR) modified glassy carbon electrode. Here, [Cu(phen)2](2+) acted advantageously as both the electrochemical indicator and the
Hongwei Chen et al.
ACS applied materials & interfaces, 7(23), 12814-12823 (2015-05-27)
Although many techniques exist for fabricating near-infrared (NIR)-resonant and magnetic resonance imaging (MRI)-capable nanomediators for photothermal cancer therapy, preparing them in an efficient and scalable process remains a significant challenge. In this report, we exploit one-step siloxane chemistry to facilely
Sarah Louise Dombernowsky et al.
Nature communications, 6, 7518-7518 (2015-06-26)
The metalloproteinase ADAM17 activates ErbB signalling by releasing ligands from the cell surface, a key step underlying epithelial development, growth and tumour progression. However, mechanisms acutely controlling ADAM17 cell-surface availability to modulate the extent of ErbB ligand release are poorly
Ana L M Ivan et al.
Journal of photochemistry and photobiology. B, Biology, 138, 124-133 (2014-06-14)
Ultraviolet B (UVB) irradiation may cause oxidative stress- and inflammation-dependent skin cancer and premature aging. Pyrrolidine dithiocarbamate (PDTC) is an antioxidant and inhibits nuclear factor-κB (NF-κB) activation. In the present study, the mechanisms of PDTC were investigated in cell free
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