MABT63

Anti-Nectin-3/PVRL3 (CD113) Antibody, clone N3.12.4

clone N3.12.4, from mouse

• Sinónimos: poliovirus receptor-related 3, poliovirus receptor-related protein 3, nectin 3, nectin-3, Nectin-3, CD113 antigen
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: N3.12.4, monoclonal
• reactividad de especies: human
• técnicas: flow cytometry: suitable
• isotipo: IgG2aκ
• Nº de acceso NCBI: NP_056295
• Nº de acceso UniProt: Q9NQS3
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... NECTIN3(25945)

Descripción

Descripción general

Nectin-3, also known as Poliovirus receptor-related protein 3 (PVRL3) and PRR3, is thought to work with cadherin to form cell-cell adherens junctions. It is a transmembrane protein that is commonly found in the testis and in placental tissue. Nectin-3 colocalizes with CD155, the cognate receptor for poliovirus, to cell-cell junctions. Nectin-3′s involvement in down-regulation PVR from the cell surface leads to a reduction in cell motility and proliferation.

Inmunógeno

Full length recombinant protein corresponding to human Nectin-3.

Aplicación

Anti-Nectin-3/PVRL3 (CD113) Antibody, clone N3.12.4 detects level of Nectin-3/PVRL3 (CD113) & has been published & validated for use in FC.

Research Category
Cell Structure

Research Sub Category
ECM Proteins

Calidad

Evaluated by Flow Cytometry in U251 cells.

Flow Cytometry Analysis: 0.1 µg of this antibody detected Nectin-3 in U251 cells.

Descripción de destino

61 kDa calculated

Forma física

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
U251 cells

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable