MAB4356A4

Anti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor^™ 488 conjugate

clone 6C1.2, from mouse, ALEXA FLUOR^™ 488

• Sinónimos: Pluripotent embryonic stem cell-related gene 1 protein, developmental pluripotency associated 2
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• biological source: mouse
• Quality Level: 100
• conjugate: ALEXA FLUOR^™ 488
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 6C1.2, monoclonal
• species reactivity: mouse
• technique(s): immunocytochemistry: suitable
• NCBI accession no.: NP_082891
• UniProt accession no.: Q9CWH0
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: mouse ... Dppa2(73703)

Descripción

General description

DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells.

Immunogen

recombinant protein corresponding to mouse DPPA-2.

Application

Research Category
Stem Cell Research

Research Sub Category
Pluripotent & Early Differentiation

This Anti-DPPA-2 Antibody, clone 6C1.2, Alexa Fluor 488 conjugate is validated for use in ICC for the detection of DPPA-2.

Quality

Evaluated by Immunocytochemistry in Mouse Embryonic Stem Cells (SCR012). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected SOX-2 in Mouse Embryonic Stem Cells (SCR012).

Target description

~30 kDa observed

Physical form

Protein G Purified

Purified mouse monoclonal IgG2aλ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.

Analysis Note

Control
Mouse Embryonic Stem Cells (SCR012).

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable