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MAB1973Z

Sigma-Aldrich

Anti-Integrin α1 Antibody, clone FB12, azide free

clone FB12, Chemicon®, from mouse

Sinónimos:

CD49a, MAB1973

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100 μG
$498.00

$498.00


Fecha estimada de envío11 de abril de 2025


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100 μG
$498.00

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

$498.00


Fecha estimada de envío11 de abril de 2025


Solicitar un pedido a granel

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

FB12, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ITGA1(3672)

Specificity

Reacts with the I domain (Val151 - Ala364) of human alpha1 integrin (Fabbri, 1996). Precipitates proteins of Mr 180 kDa, pI 5.9-6.0 (alpha chain) and Mr 115 kDa, pI 4.5-5.0 (beta chain) from human lymphocyte lysates (Zocchi, 1991). Does not recognize recombinant I domain of rat integrin alpha1.

Application

Detect Integrin α1 using this Anti-Integrin α1 Antibody, clone FB12, azide free validated for use in ELISA, FC, IH, IP, FUNC & WB.
Immunohistochemistry: 2 μg/mL, with paraformaldehyde fixation. Immunoblotting: 2 μg/mL

Immunoprecipitation: 1 μg/mL

FACS analysis: 2 μg/mL

ELISA: 0.5 μg/mL

Inhibition of activated human lymphocyte binding to laminin, collagen IV and fibronectin (Fabbri, 1996): 1-5 μg/mL

Optimal working dilutions must be determined by end user.

Target description

130 kDa

Physical form

Format: Purified
Purified immunoglobulin in 0.02M PB, pH 7.6, 0.25M NaCl.

Analysis Note

Control
Microvascular endothelium

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Recent technological advances in single-cell genomics make it possible to analyze cellular heterogeneity of tumor samples. Here, we applied single-cell RNA-seq to measure the transcriptomes of 307 single cells cultured from three biopsies of three different patients with a BRAF/NRAS
Integrin upregulation and localization to focal adhesion sites in pregnant human myometrium.
Burkin, HR; Rice, M; Sarathy, A; Thompson, S; Singer, CA; Buxton, IL
Reproductive Sciences null
Integrin ?5?1 facilitates cancer cell invasion through enhanced contractile forces.
Mierke, CT; Frey, B; Fellner, M; Herrmann, M; Fabry, B
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Richard A Que et al.
Journal of biomedical materials research. Part A, 106(5), 1363-1372 (2018-01-18)
Adhesion to the microenvironment profoundly affects stem cell functions, including proliferation and differentiation, and understanding the interaction of stem cells with the microenvironment is important for controlling their behavior. In this study, we investigated the effects of the integrin binding

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