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MilliporeSigma

APT750

ApopNexin Annexin V FITC Apoptosis Kit

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UNSPSC Code:
12161503
NACRES:
NA.45
eCl@ss:
32161000
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species reactivity

mammals

Quality Segment

technique(s)

flow cytometry: suitable

UniProt accession no.

detection method

fluorometric

General description

FUNCTION: SwissProt: P08758 # This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
SIZE: 320 amino acids; 35937 Da
SUBUNIT: Monomer. Binds ATRX (By similarity).
DOMAIN: SwissProt: P08758 A pair of annexin repeats may form one binding site for calcium and phospholipid.
SIMILARITY: Belongs to the annexin family. & Contains 4 annexin repeats.

Preparation Note

ApopNexin FITC Apoptosis Detection Kit should be stored at 2-8°C and protected from light. Precautions · For research use only. Not for use in diagnostic procedures. · Part no. APT750a contains 0.02% sodium azide. · Part no. APT750c contains Propidium Iodide (PI), a suspected carcinogen. Handle with care using gloves and eye protection; do not ingest or contact to skin.

Other Notes

Component / Part No. / Quantity / Storage ApopNexin FITC / APT750a / 0.5 mL / 2-8°C Binding Buffer, 4X / APT750b / 50 mL / 2-8°C Propidium Iodide (PI), 20 μg/mL / APT750c / 1.6 mL / 2-8°C

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


Clase de almacenamiento

10 - Combustible liquids



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Contenido relacionado

Evading Apoptosis: Cell Based Assays. As leaders in cancer research, EMD Millipore scientists have developed a wide range of assays and reagents to help uncover apoptosis mechanisms and possible ways to induce apoptosis in tumor cells for therapeutic benefit.

"Cells maintain a healthy state by delicately balancing multiple processes and signaling pathways. Only by studying all of these facets of cell health can we accurately characterize the state of a cell under specified conditions. Diverse inputs, such as disease states, nutrient availability, cell-cell contacts, extracellular matrix, tissue microenvironment, oxygen content, developmental cues, or various forms of cellular stress can shift the balance of cell health pathways. Therefore, a multipronged approach using complementary analysis platforms and technologies is necessary for a complete picture of cell health. In addition to using cell health assessment for elucidating disease mechanisms and therapeutic discovery, monitoring key indicators of cell health and performance (such as the apoptotic fraction, viability, cell cycle, cell counts, and transfection efficiency) helps establish uniform standards of cellular performance across long-term research studies. Knowing the performance profile of your cells prior to running your bioassay can mean the difference between valid assay results and wasted reagents, lost time and discarded data."






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SKUGTIN
APT75008436037125126