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ABN442

Sigma-Aldrich

Anti-FGF-20 Antibody

from rabbit, purified by affinity chromatography

Sinónimos:

Fibroblast growth factor 20, FGF-20

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

species reactivity (predicted by homology)

guinea pig (based on 100% sequence homology), ferret (based on 100% sequence homology), mouse (based on 100% sequence homology), rat (based on 100% sequence homology)

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... FGF20(26281)

General description

FGF-20 is a recent but important neurotrophic factor that regulates multiple central nervous system developmental systems and cell functions. It is a secreted protein expressed most highly in the cerebellum but also found in other regions. FGF-20 is a pro-survival factor on neurons and specifically has been shown to protect dopaminergic neurons against a range of toxic insults in vitro, through activation of fibroblast growth factor receptor 1 (FGFR1). FGF-20 treatments also appear to protect neurons in various disease models so it is being studied as a possible therapy.

Immunogen

KLH-conjugated linear peptide corresponding to human FGF-20 near theC-terminal.

Application

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected FGF-20 in human cerebral cortex, human cerebellum, and human thalamus tissue.
This Anti-FGF-20 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of FGF-20.

Quality

Evaluated by Western Blotting in transfected HEK293 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected FGF-20 in 10 µg of transfected HEK293 cell lysate.

Target description

~30 kDa observed. Uncharacterized band(s) may appear in some lysates.

Other Notes

Concentration: Please refer to lot specific datasheet.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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