ABC335

Anti-MTCH2 Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: MTCH2, Mitochondrial carrier homolog 2, HSPC032, MIMP, Met-induced mitochondrial protein
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: mouse, human
• técnicas: immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• Nº de acceso UniProt: Q9Y6C9
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... MTCH2(23788)

Descripción

Descripción general

Mitochondrial carrier homolog 2 (MTCH2) may play a key role in the mitochondrial apoptosis pathway and may induce mitochondrial depolarization. MTCH2 is suggested to catalyze the exchange of substrates across the inner mitochondrial membrane in response to apoptotic signals. Additionally, it is suggested to be targeted by Bid, a pro-apoptotic Bcl-2 family member. The Bcl-2 family of proteins incorporates a number of critical regulators of apoptosis that can be divided into two classes: inhibitors of apoptosis and promoters of cell death. Apoptosis plays a major role in tissue homeostasis, normal organism development, and removal of damaged cells. The disruption of this process has been linked to a variety of diseases such as cancer.

Inmunógeno

KLH-conjugated linear peptide corresponding to human MTCH2.

Aplicación

Anti-MTCH2 Antibody is a highly specific rabbit polyclonal antibody, that targets Mitochondrial carrier homolog 2 & has been tested in western blotting, IHC & Immunofluorescence.

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected MTCH2 in mouse kidney tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected MTCH2 in mouse kidney cells.

Calidad

Evaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected MTCH2 in 15 µg of HEK293 cell lysate.

Descripción de destino

~34 kDa observed.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable