The solubility of gonadorelin (acetate) in ethanol is roughly 0.25 mg/ml and about 30 mg/ml in DMSO and DMF.
869003-M
Luteinizing Hormone, Human Pituitary, Iodination Grade
Sinónimos:
Luteinizing Hormone, Human Pituitary, Iodination Grade, hLH
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10 μG
$166.00
50 μG
$605.00
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10 μG
$166.00
50 μG
$605.00
About This Item
Productos recomendados
origen biológico
human
Nivel de calidad
descripción
Merck USA index - 14, 5613
Ensayo
≥95% (weight)
Formulario
solid
fabricante / nombre comercial
Calbiochem®
condiciones de almacenamiento
OK to freeze
impurezas
≤0.05% hCG
≤0.5% hFSH, hTSH
color
white
solubilidad
water: 1 mg/mL
temp. de almacenamiento
−20°C
Descripción general
Native, human luteinizing hormone from pituitary gland. Heterodimeric glycoprotein hormone secreted by the anterior pituitary gland that is required for ovulation, spermatogenesis, and the biosynthesis of sex steroids. Regulates biosynthesis and/or secretion of sex steroids. In the female, LH stimulates synthesis of progesterone in the ovaries, release of estrogen from Graafian follicles, induction of ovulation, and formation of the corpus luteum. In the male, LH stimulates testosterone secretion by the testes. Biological specificity has been attributed to the β-chain.
Acciones bioquímicas o fisiológicas
≥ 5,000 IU/mg
Advertencia
Toxicity: Carcinogenic / Teratogenic (D)
Otras notas
Ramanujam, L.N., et al. 1999. Clin. Endocrinol.51, 243.
Información legal
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Could you please provide instructions on how to reconstitute product number 869003, specifically Luteinizing Hormone, Human Pituitary, Iodination Grade?
1 answer-
Helpful?
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Hello, Can this iodination grade hLH be used in rat LH radioimmunoassay or do you carry any iodination grade rLH?
1 answer-
The suitability of this product in rat studies has not been determined. It has been shown that iodination may lower the potency of LH and a lower affinity to hormonal receptors. It may be helpful to view a similar product L6420. Again, this product has not been tested for suitability in rat.
Below are some references that may be helpful in determining if these products would be suitable for the specified application.1. Effect of Iodination on the Biological Activity and Metabolism of Human Luteinizing Hormone
https://academic.oup.com/jcem/article-abstract/28/5/613/27156322. Iodination of Luteinizing Hormone-Releasing Hormone
https://pubs.acs.org/doi/pdf/10.1021/bi00553a0063. Species specificity in the response of an in vitro amphibian (Xenopus laevis) ovulation assay to mammalian luteinizing hormones
https://www.sciencedirect.com/science/article/pii/0016648076900393Helpful?
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