The highest test point found is that the substance is soluble in DMSO at a concentration of 50 mg/ml.
481981
Nifedipine
≥98% (UV), L-type Ca2+ channel bocker, solid
Sinónimos:
Nifedipine, L-Type Calcium Channel Blocker III
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250 MG
$91.20
Acerca de este artículo
Fórmula empírica (notación de Hill):
C17H18N2O6
Número CAS:
Peso molecular:
346.33
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
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Permítanos ayudarleNombre del producto
Nifedipine, Relatively selective blocker of L-type Ca2+ channels.
SMILES string
[N+](=O)([O-])c1c(cccc1)C2C(=C(NC(=C2C(=O)OC)C)C)C(=O)OC
InChI
1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3
InChI key
HYIMSNHJOBLJNT-UHFFFAOYSA-N
description
Merck USA index - 14, 6528
assay
≥98% (UV)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
yellow
solubility
DMSO: soluble, ethanol: soluble
shipped in
ambient
storage temp.
10-30°C
Quality Level
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Categorías relacionadas
1 of 4
Este artículo | |||
|---|---|---|---|
| assay ≥98% (UV) | assay - | assay - | assay - |
| form solid | form - | form - | form solid |
| manufacturer/tradename Calbiochem® | manufacturer/tradename - | manufacturer/tradename EDQM | manufacturer/tradename BP |
| Quality Level 100 | Quality Level 300 | Quality Level - | Quality Level - |
| storage temp. 10-30°C | storage temp. 2-30°C | storage temp. - | storage temp. 2-8°C |
| storage condition OK to freeze, protect from light | storage condition - | storage condition - | storage condition - |
General description
Relatively selective blocker of L-type Ca2+ channels. One of the most extensively studied blockers of 1,4-dihydropyridine-type Ca2+ channels, and a pharmacologically-useful vasodilator. Induces apoptosis in human glioblastoma cells.
Biochem/physiol Actions
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
L-type Ca2+ channels
L-type Ca2+ channels
Preparation Note
Following reconstitution, refrigerate (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Reid, K., et al. 1997. J. Pharmacol. Exp. Ther. 283, 993.
Kondo, S., et al. 1995. J. Neurosurg.82, 469.
Antkiewicz-Michaluk, L., et al. 1994. Eur. J. Pharmacol. 254, 9.
Calabresi, P., et al. 1994. J. Neurosci. 14, 4871.
Akman, M.S., et al. 1993. Endocrinology132, 1286.
Cirillo, M., et al. 1993. Circ. Res.72, 847.
Young, R.J., et al. 1993. Biochim. Biophys. Acta1146, 81.
Janis, R., et al. 1987. Adv. Drug Res.16, 311.
Kondo, S., et al. 1995. J. Neurosurg.82, 469.
Antkiewicz-Michaluk, L., et al. 1994. Eur. J. Pharmacol. 254, 9.
Calabresi, P., et al. 1994. J. Neurosci. 14, 4871.
Akman, M.S., et al. 1993. Endocrinology132, 1286.
Cirillo, M., et al. 1993. Circ. Res.72, 847.
Young, R.J., et al. 1993. Biochim. Biophys. Acta1146, 81.
Janis, R., et al. 1987. Adv. Drug Res.16, 311.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Could you please provide the upper limit of saturation in DMSO for item 481981, Nifedipine?
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