This Anti-Nitrotyrosine Antibody, clone 1A6, Alexa Fluor 488 conjugate is validated for use in FC, WB for the detection of Nitrotyrosine.
Calidad
Routinely evaluated by immunoblot.
Forma física
Protein G Purified mouse monoclonal in a solution of 1% BSA, PBS, 0.05% Tween, and 0.05% sodium azide as a preservative.
Almacenamiento y estabilidad
Stable for 1 year at 2–8°C from date of shipment in undiluted aliquots. Upon receipt, and prior to removing the cap, centrifuge the vial to remove any material in the cap. DO NOT FREEZE. Store at 2–8°C in aliquots, in the dark. Avoid repeated warming/cooling cycles.
Otras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Información legal
ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Biological selectivity and functional aspects of protein tyrosine nitration.
Ischiropoulos, Harry
Biochemical and biophysical research communications, 305, 776-783 (2003)
Compartmentalized nitrosation and nitration in mitochondria.
Ghafourifar, Pedram and Colton, Carol A
Antioxidants & Redox Signaling, 5, 349-354 (2003)
Relevance of protein nitration in brain injury: a key pathophysiological mechanism in neurodegenerative, autoimmune, or inflammatory CNS diseases and stroke.
The Journal of cell biology, 193(5), 867-884 (2011-06-01)
Atherosclerosis is readily observed in regions of blood vessels where disturbed blood flow (d-flow) is known to occur. A positive correlation between protein kinase C ζ (PKCζ) activation and d-flow has been reported, but the exact role of d-flow-mediated PKCζ
Peroxynitrite is increasingly proposed as a contributor to defence system in marine bivalve. It can be formed by combination of superoxide and nitric oxide, and can react with tyrosine residues of proteins giving rise to 3-nitrotyrosine. The present article describes
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