14-700

NEK11 Protein, active, 10 µg

• Código UNSPSC: 12352202
• eCl@ss: 32160405

Propiedades

• recombinante: expressed in baculovirus infected Sf21 cells
• Nivel de calidad: 100
• descripción: protein target NEK11
• purificado por: (Ni²⁺/NTA-agarose)
• técnicas: activity assay: suitable
• Nº de acceso UniProt: Q8NG66
• Información sobre el gen: human ... NEK11(79858)

Descripción

Descripción general

FUNCTION: SwissProt: Q8NG66 # Possible role in S-phase checkpoint mechanism.
COFACTOR: Manganese or magnesium.
SIZE: 645 amino acids; 74162 Da
SUBCELLULAR LOCATION: Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S- arrested cells.
TISSUE SPECIFICITY: Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
DEVELOPMENTAL STAGE: Predominantly expressed at S/G2/M phase.
PTM: Phosphorylated.
SIMILARITY: SwissProt: Q8NG66 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. NIMA subfamily. & Contains 1 protein kinase domain.

Calidad

routinely evaluated by phosphorylation of MBP (Catalog # 13-104)

Propiedades físicas

59.3kDa

Almacenamiento y estabilidad

6 months at -70°C from date of shipment

Nota de análisis

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H317
• Consejos de prudencia: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Clasificaciones de peligro: Skin Sens. 1
• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable