14-1048
Human recombinant CARM1
Human recombinant CARM1 with an N-terminal FLAG tag expressed in FreeStyle 293-F cells.
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About This Item
Código UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.41
recombinante
expressed in FreeStyle™ 293-F cells
Nivel de calidad
mol peso
Mw ~66 kDa
fabricante / nombre comercial
Upstate®
técnicas
activity assay: suitable (histone methyltransferase (HMT))
Nº de acceso NCBI
Nº de acceso UniProt
Condiciones de envío
dry ice
Información sobre el gen
human ... CARM1(10498)
Descripción general
Product Source: Human
Aplicación
Human recombinant CARM1 with an N-terminal FLAG tag expressed in FreeStyle 293-F cells.
Research Category
Nuclear Function
Nuclear Function
Calidad
routinely evaluated by methylation of histone H3
Ligadura / enlace
Replaces: 14-575
Almacenamiento y estabilidad
6 months at -80°C.
Otras notas
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Varies by lot; see lot-specific datasheet for information on each lot.
Información legal
FreeStyle is a trademark of Invitrogen Corp.
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Melody D Fulton et al.
The Journal of biological chemistry, 297(4), 101123-101123 (2021-09-08)
Histone arginine methylation is a key post-translational modification that mediates epigenetic events that activate or repress gene transcription. Protein arginine methyltransferases (PRMTs) are the driving force for the process of arginine methylation, and the core histone proteins have been shown
Hongwei Li et al.
The Journal of biological chemistry, 277(47), 44623-44630 (2002-09-19)
The RNA-binding protein HuR stabilizes labile mRNAs carrying AU-rich instability elements. This mRNA stabilization can be induced by hypoxia, lipopolysaccharide, and UV light. The mechanism by which these stimuli activate HuR is unclear and might be related to post-translational modification
Seth Frietze et al.
Cancer research, 68(1), 301-306 (2008-01-04)
Estrogen receptor alpha (ER alpha) mediates breast cancer proliferation through transcriptional mechanisms involving the recruitment of specific coregulator complexes to the promoters of cell cycle genes. The coactivator-associated arginine methyltransferase CARM1 is a positive regulator of ER alpha-mediated transcriptional activation.
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