07-167
Anti-Blys/TALL-1/BAFF/THANK Antibody
Upstate®, from rabbit
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... TNFSF13B(10673)
Specificity
Blys/TALL-1/BAFF/THANK
Immunogen
peptide corresponding to amino acids 254-269 of human Blys (EEGDELQLAIPRENAQ)
Application
Anti-Blys/TALL-1/BAFF/THANK Antibody is an antibody against Blys/TALL-1/BAFF/THANK for use in WB.
Quality
routinely evaluated by immunoblot on RIPA lysates from Jurkat cells or HeLa nuclear extract
Target description
32kDa
Physical form
Format: Purified
PBS containing 0.05% BSA and 0.05% sodium azide.
Analysis Note
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases.
Scapini, P; Carletto, A; Nardelli, B; Calzetti, F; Roschke, V; Merigo, F; Tamassia et al.
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Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI.
Weifeng Xu, Bing He, April Chiu, Amy Chadburn, Meimei Shan, Malwina Buldys, Aihao Ding et al.
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Patrizia Scapini et al.
The Journal of experimental medicine, 197(3), 297-302 (2003-02-05)
B lymphocyte stimulator (BLyS) is a novel member of the TNF ligand superfamily that is important in B cell maturation and survival. We demonstrate that human neutrophils, after incubation with G-CSF or, less efficiently, IFN gamma, express high levels of
Macrophage- and dendritic cell--dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF.
Craxton, A; Magaletti, D; Ryan, EJ; Clark, EA
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F Mackay et al.
The Journal of experimental medicine, 190(11), 1697-1710 (1999-12-10)
The cause of many autoimmune and inflammatory diseases is unresolved, although dysregulated production of tumor necrosis factor (TNF) family members appears to be important in many cases. BAFF, a new member of the TNF family, binds to B cells and
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