07-1223

Anti-Protein Phosphatase 2 C α/β Antibody

from rabbit

• Sinónimos: Protein phosphatase 2C, Pyruvate dehydrogenase, Pyruvate dehydrogenase phosphatase, catalytic subunit 1, Lipoamide-phosphatase 1, mitochondrial precursor, Protein phosphatase 2C, magnesium-dependent, catalytic subunit, Pyruvate dehydrogenase (Lipoamide)
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• reactividad de especies: bovine, human, rat
• reactividad de especies (predicha por homología): mouse
• técnicas: western blot: suitable
• Nº de acceso UniProt: Q9P0J1
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... PDP1(54704)

Descripción

Descripción general

PP-2 C α/β is heterodimer located in the mitochondrial matrix. Within the pyruvate dehydrogenase complex, PP-2 C α/β serves to catalyze the dephosphorylation and concomitant reactivation of the E1 component’s alpha subunit. Mutations occurring in the PDP1 gene are the cause of a disease known as pyruvate dehydrogenase deficiency (PDP deficiency), which leads to neurological dysfunction from lactic acidosis.

Especificidad

Recognizes the alpha/beta regulatory subunit isotype of protein phosphatase 2C (PP2C). PP 2C alpha/beta polyclonal antibody binds a 44-46 kDa protein.

Inmunógeno

Purified peptide conjugated to KLH.

Aplicación

Detect Protein Phosphatase 2 C α/β using this Anti-Protein Phosphatase 2 C α/β Antibody validated for use in WB.

Research Category
Signaling

Research Sub Category
Kinases & Phosphatases

Calidad

Evaluated by Western Blot in L6 cell lysates.
Western Blot Analysis: 1:500 dilution of this lot detected PP-2 C ALPHA/BETA on 10 ug of L6 lysates.

Descripción de destino

Approx. 46 kDa

Ligadura / enlace

Replaces: AB4090

Forma física

Format: Purified

Protein Purified

Purified immunoglobulin in phosphate buffered saline with 0.08% sodium azide.

Almacenamiento y estabilidad

Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.

Nota de análisis

Control
L6 Cell Lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable