890704C

18:1 EPC (Cl Salt)

Avanti Research^™ - A Croda Brand 890704C

• Sinónimos: 1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)
• Fórmula empírica (notación de Hill): C₄₆H₈₉NO₈PCl
• Número de CAS: 474945-24-9
• Peso molecular: 850.63
• Número MDL: MFCD22495359
• Código UNSPSC: 12352211
• NACRES: NA.25

Propiedades

• Formulario: liquid
• envase: pkg of 1 × 2.5 mL (890704C-25mg); pkg of 1 × 4 mL (890704C-100mg); pkg of 2 × 4 mL (890704C-200mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand 890704C
• concentración: 10 mg/mL (890704C-25mg); 25 mg/mL (890704C-100mg); 25 mg/mL (890704C-200mg)
• tipo de lípido: transfection; cationic lipids
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)OCC.[Cl-]
• Clave InChI: LXTQBOAODSPEHG-NATHRRJOSA-M

Descripción

Descripción general

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) is a cationic alkylated phospholipid.[1]

Aplicación

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt) (18:1 EPC (Cl Salt)) is suitable:

• for composing lipid shell to prepare lipopolyplex/mRNA vaccine[2]
• in solvent-assisted preparation of supported lipid bilayers[3]
• along with 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) in mixed liposomes as colloidal vectors for physicochemical study of the DNA compaction[1]
• to formulate the lipid nanoparticle (LNP1) to enhance intracellular delivery mediated by shock waves[4]

Acciones bioquímicas o fisiológicas

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) serves as a transfection reagent. 18:1 EPC is applicable in liposomes and lipoplexes. It is a potential vector in gene therapy.[1]

Envase

5 mL Clear Glass Sealed Ampule (890704C-100mg)

5 mL Clear Glass Sealed Ampule (890704C-200mg)

5 mL Clear Glass Sealed Ampule (890704C-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H302,H315,H319,H331,H336,H351,H361d,H372
• Consejos de prudencia: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Órganos de actuación: Liver,Kidney, Respiratory system
• Código de clase de almacenamiento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): does not flash
• Punto de inflamabilidad (°C): does not flash