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855776C

Avanti

19:0 Lyso PC

Avanti Research™ - A Croda Brand 855776C

Sinónimos:

1-nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine

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About This Item

Fórmula empírica (notación de Hill):
C27H56NO7P
Número de CAS:
108273-88-7
Peso molecular:
537.71
Número MDL:
MFCD00672604
Código UNSPSC:
51191904
NACRES:
NA.25

Ensayo

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

Formulario

liquid

envase

pkg of 1 × 2.5 mL (855776C-25mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand 855776C

concentración

10 mg/mL (855776C-25mg)

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Descripción general

Lysophosphatidylcholine (LPC) is a bioactive proinflammatory lipid secreted on pathological response.[1] It has a choline group at its polar head.[2]

Aplicación

19:0 Lyso PC has been used for the quantification of lysophosphatidylcholine (LPC) in microsomes by mass spectrometry.[3] It has also been used for plasma lipidome analysis of cows.[4]

Acciones bioquímicas o fisiológicas

Lysophosphatidylcholine (LPC) modifies various biological functions in different cell-types, like endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. It is associated with atherosclerosis and inflammatory diseases. LPC stimulates many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases.[1]

Envase

5 mL Clear Glass Sealed Ampule (855776C-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órganos de actuación

Central nervous system, Liver,Kidney

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

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Architecture of lipid droplets in endoplasmic reticulum is determined by phospholipid intrinsic curvature
Choudhary V, et al.
Current Biology, 28(6), 915-926 (2018)
Altered plasma lipidome profile of dairy cows with fatty liver disease
Gerspach C, et al.
Research in Veterinary Science, 110, 47-59 (2017)
Ruichuan Yin et al.
Nature protocols, 14(12), 3445-3470 (2019-11-15)
Mass spectrometry imaging (MSI) enables label-free spatial mapping of hundreds of biomolecules in tissue sections. This capability provides valuable information on tissue heterogeneity that is difficult to obtain using population-averaged assays. Despite substantial developments in both instrumentation and methodology, MSI
Sidra Iqbal et al.
Plant physiology and biochemistry : PPB, 147, 101-112 (2019-12-20)
Plant phospholipase A (PLA) and C (PLC) families are least explored in terms of structure, diversity and their roles in membrane lipid remodeling under stress conditions. In this study, we performed gene family analysis, determined gene expression in different tissues
Marco Custódio et al.
Scientific reports, 10(1), 6583-6583 (2020-04-22)
Halophytes are increasingly regarded as suitable extractive species and co-products for coastal Integrated Multi-Trophic Aquaculture (IMTA) and studying their lipidome is a valid means towards their economic valorization. Halimione portulacoides (L.) Aellen edible leaves are rich in functional lipids with
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