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MilliporeSigma

840037P

Avanti

16:0 PS

Avanti Research - A Croda Brand

Sinónimos:

1,2-dihexadecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DPPS; PS(16:0/16:0); 110668

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About This Item

Fórmula empírica (notación de Hill):
C38H73NO10PNa
Número de CAS:
Peso molecular:
757.95
Número MDL:
Código UNSPSC:
51191904
NACRES:
NA.25

descripción

1,2-dipalmitoyl-sn-glycero-3-phospho-L-serine (sodium salt)

Ensayo

>99% (TLC)

Formulario

powder

envase

pkg of 1 × 10 mg (840037P-10mg)
pkg of 1 × 200 mg (840037P-200mg)
pkg of 1 × 25 mg (840037P-25mg)
pkg of 1 × 500 mg (840037P-500mg)

fabricante / nombre comercial

Avanti Research - A Croda Brand

tipo de lípido

phospholipids
cardiolipins

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C38H74NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(40)46-31-34(32-47-50(44,45)48-33-35(39)38(42)43)49-37(41)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h34-35H,3-33,39H2,1-2H3,(H,42,43)(H,44,45);/q;+1/p-1/t34-,35+;/m1./s1

Clave InChI

GTLXLANTBWYXGW-CEGNZRHUSA-M

Descripción general

Phosphatidylserine (PtdSer) is an anionic phospholipid abundantly present in the eukaryotic cell. 10% of the total cellular lipid consists of phosphatidylserine.[1] O‐phospho‐L‐serine is a heat‐stable substrate.[2]

Aplicación

16:0 PS has been used in the assay to measure interactions between purified dynamin-related protein 1 (Drp1) and synthetic liposomes.[3]
16:0 PS may be used in liposome flotation assay to measure its interactions between purified dynamin related protein 1 (Drp1)[4] and as a component in the lipid mixtures to prepare lipid monolayers.[5] It has also been used to prepare liposomes by the lipid film hydration method.[6]

Acciones bioquímicas o fisiológicas

Phosphatidylserine (PtdSer) participates in various intracellular signaling pathways. It also play a major role in apoptosis and blood clotting.[1]

Envase

20 mL Clear Glass Screw Cap Vial (840037P-200mg)
30 mL Amber Wide Mouth Bottle with Screw Cap (840037P-500mg)
5 mL Amber Glass Screw Cap Vial (840037P-10mg)
5 mL Amber Glass Screw Cap Vial (840037P-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

también adquirido normalmente con este producto

Código de clase de almacenamiento

11 - Combustible Solids


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Condensation of Model Lipid Films by Cholesterol: Specific Ion Effects
Martimathin-MA, et al.
Coatings, 9(8), 474-474 (2020)
Chelsea A Kraynak et al.
Acta biomaterialia, 108, 250-260 (2020-04-07)
Macrophages play a critical role in the initiation, maintenance, and resolution of inflammation because of their diverse and plastic phenotypic responses to extracellular stimuli. Inflammatory stimuli drive the recruitment and activation of inflammatory (M1) macrophages, capable of significant cytokine production
Assay to Measure Interactions between Purified Drp1 and Synthetic Liposomes
Adachi Y, et al.
Bio-protocol, 7(9) (2017)
Koshiki Mino et al.
FEBS letters, 551(1-3), 133-138 (2003-09-11)
O-Acetylserine sulfhydrylase (OASS), a pyridoxal 5'-phosphate (PLP)-dependent enzyme, catalyzes the synthesis of L-cysteine from O-acetyl-L-serine and sulfide. O-Acetyl-L-serine is labile at high temperatures at which hyperthermophilic archaea live. Herein, a study of the substrate specificity of OASS from Aeropyrum pernix
Ana Cristina Racca et al.
Frontiers in oncology, 9, 544-544 (2019-07-06)
Tumor cells require high rates of lipid synthesis to support membrane biogenesis for their exacerbated growth. The only two proteins known that activate phospholipid synthesis are Fra-1 and c-Fos, two members of the AP-1 family of transcription factors. These proteins

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