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700175P

Avanti

Brassicasterol

Avanti Research™ - A Croda Brand

Sinónimos:

24-Methyl cholest-5,22-dien-3β-ol

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About This Item

Fórmula empírica (notación de Hill):
C28H46O
Número de CAS:
474-67-9
Peso molecular:
398.66
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (700175P-5MG)

manufacturer/tradename

Avanti Research™ - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

CC1(CC[C@H](O)C2)C2=CCC3C1CCC4(C)C3CCC4C(/C=C/[C@H](C)C(C)C)C

InChI

1S/C28H46O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-9,18-20,22-26,29H,10-17H2,1-6H3/b8-7+/t19-,20+,22-,23-,24+,25-,26-,27-,28+/m0/s1

InChI key

OILXMJHPFNGGTO-ZAUYPBDWSA-N

General description

Brassicasterol is a plant sterol, sharing similar structure with cholesterol. It is obtained through the dietary sources, including sea food.

Application


  • Deciphering the effect of phytosterols on Alzheimer′s disease and Parkinson′s disease: the mediating role of lipid profiles: This research demonstrates the neuroprotective potential of phytosterols, including Brassicasterol, in modulating lipid profiles to mitigate symptoms of neurodegenerative diseases such as Alzheimer′s and Parkinson′s (Guo et al., 2024).

  • Liposomal Phytosterols as LDL-Cholesterol-Lowering Agents in Diet-Induced Hyperlipidemia: Discusses the effectiveness of Brassicasterol and other phytosterols encapsulated in liposomes for reducing LDL cholesterol, showcasing a potential therapeutic approach in hyperlipidemia management (Poudel et al., 2023).

  • Sterol Regulation of Development and 20-Hydroxyecdysone Biosynthetic and Signaling Genes in Drosophila melanogaster: Highlights the role of Brassicasterol in regulating developmental and hormonal pathways in model organisms, suggesting implications for developmental biology studies (Wen et al., 2023).

Biochem/physiol Actions

Brassica sterol in cerebrospinal fluid might serve as an indicator for Alzheimer′s disease. It is found in rapeseed oil. Brassicasterol is thus, useful in identifying brassica oil and contamination of rapeseed and canola oil in others. Plant sterols can penetrate through the blood brain barrier.

Packaging

5 mL Amber Glass Screw Cap Vial (700175P-5MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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The plant sterol brassicasterol as additional CSF biomarker in Alzheimer?s disease
Vanmierlo T, et al.
Acta Psychiatrica Scandinavica, 124(3), 184-192 (2011)
The search of new biomarkers to identify Alzheimer?s disease: An editorial comment to T. Vanmierlo et al.`The plant sterol brassicasterol and additional CFS biomarker in Alzheimer?s Disease?(1)
Lobo A and Quintanilla MA
Acta Psychiatrica Scandinavica, 124(3), 163-164 (2011)
Rapeseed and Canola Oil: Production, Processing, Properties and Uses, 60-60 (2004)
Analysis of sterol compounds from Sambucus ebulus
Bubulica MV, et al.
Chemistry of Natural Compounds, 1-2 (2012)

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