CDS022536

Lenalidomide

• Sinónimos: 3-(7-Amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
• Fórmula empírica (notación de Hill): C₁₃H₁₃N₃O₃
• Peso molecular: 259.26
• Número MDL: MFCD07772307
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329795811

Propiedades

• descripción: Aldrich^CPR
• Formulario: powder
• cadena SMILES: O=C1N(C2CCC(NC2=O)=O)CC3=C1C=CC=C3N
• InChI: 1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
• Clave InChI: GOTYRUGSSMKFNF-UHFFFAOYSA-N
• Información sobre el gen: human ... CRBN(51185) , CUL4A(8451) , DDB1(1642) , RBX1(9978)

Descripción

Aplicación

Lenalidomide is a structural analog of thalidomide, which exhibits excellent anticancer activity against multiple myeloma.[1][2] It can be used in synthesizing multiple derivatives of lenalidomide to study their biological activity.[3] Synthesis of gelator containing lenalidomide, which forms stable gels in 1,4-dioxane has been reported.[4]

Otras notas

Please note that Sigma-Aldrich provides this product to early discovery researchers as part of a collection of unique chemicals. Sigma-Aldrich does not collect analytical data for this product. Buyer assumes responsibility to confirm product identity and/or purity. All sales are final.

NOTWITHSTANDING ANY CONTRARY PROVISION CONTAINED IN SIGMA-ALDRICH′S STANDARD TERMS AND CONDITIONS OF SALE OR AN AGREEMENT BETWEEN SIGMA-ALDRICH AND BUYER, SIGMA-ALDRICH SELLS THIS PRODUCT "AS-IS" AND MAKES NO REPRESENTATION OR WARRANTY WHATSOEVER WITH RESPECT TO THIS PRODUCT, INCLUDING ANY (A) WARRANTY OF MERCHANTABILITY, (B) WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE, OR (C) WARRANTY AGAINST INFRINGEMENT OF INTELLECTUAL PROPERTY RIGHTS OF A THIRD PARTY, WHETHER ARISING BY LAW, COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OF TRADE OR OTHERWISE.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Warning
• Frases de peligro: H361d,H373
• Consejos de prudencia: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Repr. 2 - STOT RE 2
• Órganos de actuación: Blood
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable