ALD00594

2-Hydroxynicotinaldehyde

97%

• Sinónimos: 2-Hydroxy-pyridine-3-carbaldehyde, TDG4
• Fórmula empírica (notación de Hill): C₆H₅NO₂
• Número de CAS: 36404-89-4
• Peso molecular: 123.11
• MDL number: MFCD09909918
• UNSPSC Code: 12352200
• NACRES: NA.22

Propiedades

• assay: 97%
• form: powder or crystals
• reaction suitability: reaction type: C-C Bond Formation; reagent type: catalyst; reagent type: ligand; reaction type: C-H Activation
• mp: 223 °C
• functional group: aldehyde
• storage temp.: 2-8°C
• InChI: 1S/C6H5NO2/c8-4-5-2-1-3-7-6(5)9/h1-4H,(H,7,9)
• InChI key: DNTYEVWEOFZXFE-UHFFFAOYSA-N

Descripción

Application

This reagent was used as a catalytic transient directing group by Jin-Quan Yu′s lab for Pd(II)-catalyzed γ-C(sp³)-H arylation to couple free primary amines with aryl iodides. Reactions included Pd(OAc)₂ 683124 and low catalyst and directing group loading.

Citation

Pd-Catalyzed γ-C(sp³)-H Arylation of Free Amines Using a Transient Directing Group

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable