A93607
4-Azabenzimidazole
99%
Sinónimos:
1H-Imidazo[4,5-b]pyridine
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About This Item
Fórmula empírica (notación de Hill):
C6H5N3
Número de CAS:
Peso molecular:
119.12
EC Number:
MDL number:
UNSPSC Code:
12352100
eCl@ss:
32151902
PubChem Substance ID:
NACRES:
NA.22
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assay
99%
form
powder
mp
148-151 °C (lit.)
SMILES string
c1cnc2nc[nH]c2c1
InChI
1S/C6H5N3/c1-2-5-6(7-3-1)9-4-8-5/h1-4H,(H,7,8,9)
InChI key
GAMYYCRTACQSBR-UHFFFAOYSA-N
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A new method for the synthesis of dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-ones via copper(I)-catalyzed hydroamination was developed. In addition, for the first time, iodoalkynes were shown to participate in the copper(I)-catalyzed intramolecular hydroamination reaction with exclusive formation of E-isomers.
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6-Chloro-2-Aryl-1H-imidazo[4,5-b]pyridine derivatives 1-26 were synthesized and characterized by various spectroscopic techniques. All these derivatives were evaluated for their antiglycation, antioxidant and β-glucuronidase potential followed their docking studies. In antiglycation assay, compound 2 (IC50=240.10±2.50μM) and 4 (IC50=240.30±2.90μM) was found to be
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