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900629

Sigma-Aldrich

Gelatin methacryloyl

gel strength 300 g Bloom, degree of substitution 40%

Sinónimos:

GelMa, Gelatin Methacrylate, Gelatin methacrylamide

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1 G
$216.00
5 G
$899.99

$216.00

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1 G
$216.00
5 G
$899.99

About This Item

Fórmula lineal:
(C40H59N11O13)n
UNSPSC Code:
12352202
NACRES:
NA.23

$216.00

En stockDetalles

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Quality Level

100

form

powder

Storage temp.

2-8°C

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Application

Gelatin-methacrylate can be used to form crosslinked hydrogels for tissue engineering[1] and 3D printing.[2][3][4] It has been used for endothelial cell morphogenesis,[5] cardiomyocytes,[6] epidermal tissue,[7] injectable tissue constructs,[8] bone differentiation,[9] and cartilage regeneration.[10] Gelatin-methacrylate has been explored in drug delivery applications in the form of microspheres[11] and hydrogels.[12]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCT1689
MKCQ6748
MKCP7716
MKCK5644
MKCD6526

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Preparation and characterization of gelatin-poly(methacrylic acid) interpenetrating polymeric network hydrogels as a pH-sensitive delivery system for glipizide.
Gupta NV et al.
Indian Journal of Pharmaceutical Sciences, 69(1), 64-68 (2007)
Xin Zhao et al.
Advanced healthcare materials, 5(1), 108-118 (2015-04-17)
Natural hydrogels are promising scaffolds to engineer epidermis. Currently, natural hydrogels used to support epidermal regeneration are mainly collagen- or gelatin-based, which mimic the natural dermal extracellular matrix but often suffer from insufficient and uncontrollable mechanical and degradation properties. In
Anh H Nguyen et al.
Acta biomaterialia, 13, 101-110 (2014-12-03)
Gelatin has been commonly used as a delivery vehicle for various biomolecules for tissue engineering and regenerative medicine applications due to its simple fabrication methods, inherent electrostatic binding properties, and proteolytic degradability. Compared to traditional chemical cross-linking methods, such as
Chaenyung Cha et al.
Biomacromolecules, 15(1), 283-290 (2013-12-19)
Microfabrication technology provides a highly versatile platform for engineering hydrogels used in biomedical applications with high-resolution control and injectability. Herein, we present a strategy of microfluidics-assisted fabrication photo-cross-linkable gelatin microgels, coupled with providing protective silica hydrogel layer on the microgel
Kelly M C Tsang et al.
Advanced functional materials, 25(6), 977-986 (2015-09-04)
Hydrogels are often employed as temporary platforms for cell proliferation and tissue organization in vitro. Researchers have incorporated photodegradable moieties into synthetic polymeric hydrogels as a means of achieving spatiotemporal control over material properties. In this study protein-based photodegradable hydrogels
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Photo-Crosslinkable Gelatin Hydrogel: Versatile Materials for (High Resolution) Additive Manufacturing

Discussion of synthetic modifications to gelatin, improving the three-dimensional (3D) print resolution, and resulting material properties.

Three-Dimensional Bioprinting for Tissue and Disease Modeling

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

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