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760978

Sigma-Aldrich

Poly(N-isopropylacrylamide) triethoxysilane terminated

average Mn 5,000

Sinónimos:

PNIPAM silane, polyNIPAM surface modifier

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About This Item

Fórmula lineal:
(C6H11NO)nSCH2CH2CH2Si(OCH2CH3)3
Código UNSPSC:
12162002
NACRES:
NA.23

Formulario

solid

mol peso

average Mn 5,000

PDI

≤2.5

temp. de almacenamiento

2-8°C

Descripción general

Poly(N-isopropylacryamide) (PNIPAAm) is a thermoresponsive polymer. It is soluble in water below its lower critical solution temperature (LCST) (32°C) whereas it forms intramolecular hydrogen bonds thus becoming insoluble at temperatures above its LCST. PNIPAAm is functionalized with a silane coupling agent like triethoxysilane in order to reduce its surface energy thus making it hydrophobic. Triethoxysilane terminated PNIPAAm thus exhibits a switchable superhydrophobic/hydrophilic surface and are widely used as hydrophobic valves in microfluidic channels.[1]

Aplicación

  • Used in the synthesis of microspheres which are used in drug-delivery systems.[2]
  • Used in fluidic devices, in protein affinity separation, and as cell culture substrates.[3]

Características y beneficios

It exhibits swelling or deswelling behaviour with respect to external temperature which favours in nucleic acid adsorption and drug release applications.[2]

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKBZ5461V
MKBT8380V
MKBT4522V
MKBN2204V
MKBK3993V

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Poly(N-isopropyl acrylamide) carboxylic acid, thiol

Sigma-Aldrich

806366

Poly(N-isopropyl acrylamide)

mPEG20K-Silane average Mn 20000

Sigma-Aldrich

JKA3100

mPEG20K-Silane

Conformal switchable superhydrophobic/hydrophilic surfaces for microscale flow control.
Chunder, A., Etcheverry, K., Londe, G., Cho, H. J., & Zhai, L.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 333(1), 187-193 (2009)
Qiang He et al.
Langmuir : the ACS journal of surfaces and colloids, 23(7), 3981-3987 (2007-02-24)
Micro- and nanopatterns of thermosensitive poly(N-isopropylacrylamide) brush on gold substrate were prepared by using chemical lithography combined with surface-initiated atom transfer radical polymerization. Self-assembled monolayers of 4'-nitro-1, 1'-biphenyl-4-thiol were structured by chemical lithography which produced cross-linked 4'-amino-1,1'-biphenyl-4-thiol monolayer within a
Poly (N-isopropylacrylamide)-coated luminescent/magnetic silica microspheres: preparation, characterization, and biomedical applications
Guo, J., Yang, W., Wang, C., He, J., & Chen, J.
Chemistry of Materials, 18(23), 5554-5562 (2006)

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