734039

4-tert-Butyl-2,6-dimethylphenylsulfur trifluoride

• Sinónimos: Fluolead^™
• Fórmula empírica (notación de Hill): C₁₂H₁₇F₃S
• Número de CAS: 947725-04-4
• Peso molecular: 250.32
• MDL number: MFCD11858620
• UNSPSC Code: 12352002
• PubChem Substance ID: 329764866
• NACRES: NA.22

Propiedades

• form: solid
• mp: 62-68 °C
• SMILES string: Cc1cc(cc(C)c1S(F)(F)F)C(C)(C)C
• InChI: 1S/C12H17F3S/c1-8-6-10(12(3,4)5)7-9(2)11(8)16(13,14)15/h6-7H,1-5H3
• InChI key: VRTQPEYVMHATOA-UHFFFAOYSA-N

Descripción

General description

4-tert-Butyl-2,6-dimethylphenylsulfur trifluoride is a thermally stable, easy-to-handle, versatile deoxofluorinating agent that also shows high stability on contact with water. It is a superior alternative to diethylaminosulfur trifluoride (DAST).

Application

Features:

• Tolerance of many functional groups
• Highly selective functionalization
• Highly efficient and broad reaction scope
• Mild reaction conditions

Generally superior reactivity and selectivity to SF₄ and easier and safer to handle.

Shown to promote nucleophilic deoxofluorination reactions and exhibits excellent thermal stability, up to 150 °C, therefore rendering it safely applicable in a variety of processes, including industrial scale production.


Novel fluorinating reagent applicable to a variety of chemical processes (Scheme 1).

Refer to the Datasheet for more information on Fluolead^™: A Novel New Versatile Fluorinating Agent

Legal Information

Fluolead is a trademark of UBE America, Inc.

Información de seguridad

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H301,H314
• pcodes: P260 - P280 - P301 + P310 + P330 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Skin Corr. 1B
• supp_hazards: EUH014
• Storage Class: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable