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MilliporeSigma

54965

Sigma-Aldrich

(±)-3-hidroxibutirato de sodio

≥99.0% (NT)

Sinónimos:

Ácido (±)-3-hidroxibutírico sodium salt

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10 G
$62.80
50 G
$220.00

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Disponible para envío el17 de abril de 2025Detalles


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10 G
$62.80
50 G
$220.00

About This Item

Fórmula lineal:
CH3CH(OH)CH2COONa
Número de CAS:
Peso molecular:
126.09
Beilstein:
4824866
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
NACRES:
NA.22

$62.80


Disponible para envío el17 de abril de 2025Detalles


Solicitar un pedido a granel

Nivel de calidad

Ensayo

≥99.0% (NT)

mp

167-170 °C

grupo funcional

hydroxyl

cadena SMILES

[Na+].CC(O)CC([O-])=O

InChI

1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1

Clave InChI

NBPUSGBJDWCHKC-UHFFFAOYSA-M

Categorías relacionadas

Aplicación

El (±)-3-hidroxibutirato de sodio se ha utilizado en un estudio para entender el efecto del butirato sobre el factor de crecimiento de fibroblastos 21 (FGF21), que interviene en la ß-oxidación de los ácidos grasos en el hígado. [1] Puede utilizarse en la preparación del poli(3-hidroxibutirato).[2]

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Certificados de análisis (COA)

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Shengying Pan et al.
Behavioural pharmacology, 31(4), 322-332 (2020-01-03)
β-hydroxybutyrate, a ketone body metabolite, has been shown to suppress depression-like behavior in rodents. In this study, we examined its antidepressive property in acute and chronic administration modes in mice by using forced swim test and tail suspension test. Results
Roman Tyzio et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(1), 34-45 (2011-01-07)
GABA depolarizes immature neurons because of a high [Cl(-)](i) and orchestrates giant depolarizing potential (GDP) generation. Zilberter and coworkers (Rheims et al., 2009; Holmgren et al., 2010) showed recently that the ketone body metabolite DL-3-hydroxybutyrate (DL-BHB) (4 mM), lactate (4
Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.
Li H, et al.
Diabetes, 61(4), 797-806 (2012)
Novel synthesis of poly (3-hydroxybutyrate).
Juzwa M and Jedli?ski Z.
Macromolecules, 39(13), 4627-4630 (2006)
Nikolaj Rittig et al.
Shock (Augusta, Ga.), 44(1), 32-35 (2015-04-22)
Endotoxin administrations are used in experimental models of inflammatory disease. Short-term endotoxin tolerance in response to repeated endotoxin exposure is well known, but the duration of endotoxin tolerance in humans remains unknown. The main purpose of this study was to

Questions

1–4 of 4 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Is your hydroxybutyrate chemically synthesized or produced from fermentation?

    1 answer
    1. This product is produced from chemical synthesis and fermentation from cell culture. This information is presented on the lot specific Certificate of Origin. Please navigate to the ‘DOCUMENTATION’ section of the Product Detail Page to access a Certificate under the ‘Certificate of Origin’ tab:
      https://www.sigmaaldrich.com/product/aldrich/54965#product-documentation

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  4. What is the ratio of the two isomers in product 54965?

    1 answer
    1. Product 54965 is considered a racemic material, which means that there is approximately a 50/50 ratio of the two isomers. However, it is not tested or characterized, so it cannot be guaranteed to be exactly 50/50, but it should be close.

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